국가 R&D 과제 조회
과제고유번호 1711065959 당해연도 연구기간 2018-03-01 ~ 2019-02-28
과제년도 2018 총 연구기간 2017-09-01 ~ 2024-02-29
주관부처명 과학기술정보통신부 연구기관명 충북대학교
사업명 집단연구지원(R&D)
과제명 한글 종양 이환 네트워크 연구센터
영문 Cancer Predisposing Network Research Center(cPRC)
연구개발단계 기초연구 지역 충북
6T분류 BT • 보건의료관련응용 • 난치성 질환치료기술
과학기술표준분류 의약품/의약품개발기술 / 약효검색

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 1,000,000,000 370,000,000 1,370,000,000
관련 논문(76) 관련 특허(16) 관련 장비(0) 관련 보고서(0)

Identification of antioxidant constituents of the aerial part of Plantago asiatica using LC-MS/MS coupled DPPH assay
성과년도
2018
성과 고유번호
JNL-2018-00110107843
학술지명
PHYTOCHEMISTRY LETTERS
ISSN
1874-3900
Metal-free approach for the L-proline mediated synthesis of nitrones from nitrosobenzene
성과년도
2018
성과 고유번호
JNL-2018-00110108327
학술지명
TETRAHEDRON
ISSN
0040-4020
Transition-metal-free, atom-economical cascade synthesis of novel 2-sulfonated-benzo[f][1,7]naphthyridines and their cytotoxic activities
성과년도
2018
성과 고유번호
JNL-2018-00110107053
학술지명
TETRAHEDRON
ISSN
0040-4020
CXCR3-deficient natural killer cells fail to migrate to B16F10 melanoma cells
성과년도
2018
성과 고유번호
JNL-2018-00110102805
학술지명
INTERNATIONAL IMMUNOPHARMACOLOGY
ISSN
1567-5769
Phenolic amides from Tribulus terrestris and their inhibitory effects on nitric oxide production in RAW 264.7 cells
성과년도
2018
성과 고유번호
JNL-2018-00110101365
학술지명
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269
CXCR3-deficient mesenchymal stem cells fail to infiltrate into the nephritic kidney and do not ameliorate lupus symptoms in MRL.Fas(lpr) mice
성과년도
2018
성과 고유번호
JNL-2018-00110101367
학술지명
LUPUS
ISSN
0961-2033
Lathyrane-Type Diterpenoids from the Seeds of Euphorbia lathyris L. with Inhibitory Effects on NO Production in RAW 264.7 Cells
성과년도
2018
성과 고유번호
JNL-2018-00110107111
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity
성과년도
2018
성과 고유번호
JNL-2018-00110104265
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Dimeric- and trimeric sesquiterpenes from the flower of Inula japonica
성과년도
2018
성과 고유번호
JNL-2018-00110104263
학술지명
PHYTOCHEMISTRY
ISSN
0031-9422
Melanogenesis inhibitory pregnane glycosides from Cynanchum atratum
성과년도
2018
성과 고유번호
JNL-2018-00110102803
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN
0960-894X
Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Fas(lPr) Mice
성과년도
2018
성과 고유번호
JNL-2018-00110101877
학술지명
STEM CELLS INTERNATIONAL
ISSN
1687-966X
Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)-3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis
성과년도
2018
성과 고유번호
JNL-2018-00110101875
학술지명
MEDICINAL CHEMISTRY
ISSN
1573-4064
Nitric oxide inhibitory constituents from Siegesbeckia pubescens
성과년도
2018
성과 고유번호
JNL-2018-00110101363
학술지명
BIOORGANIC CHEMISTRY
ISSN
0045-2068
Novel hydroxamic acids incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)-3-hydroxyimino-indolin-2-ones: synthesis, biological evaluation, and SAR analysis
성과년도
2018
성과 고유번호
JNL-2018-00110101369
학술지명
JOURNAL OF CHEMICAL SCIENCES
ISSN
0974-3626
Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/II alpha inhibitors
성과년도
2018
성과 고유번호
JNL-2018-00110107859
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY
ISSN
0968-0896
Characterization of tyrosinase inhibitory constituents from the aerial parts of Humulus japonicus using LC-MS/MS coupled online assay
성과년도
2018
성과 고유번호
JNL-2018-00110106987
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY
ISSN
0968-0896
제2형 당뇨병성 말초신경병증을 치료하기 위한 항산화요법에 대한 고찰
성과년도
2018
성과 고유번호
JNL-2018-00110106967
학술지명
약 학 회 지
ISSN
0377-9556
alpha-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis
성과년도
2018
성과 고유번호
JNL-2018-00110107885
학술지명
THERANOSTICS
ISSN
1838-7640
Organocatalytic and Regiodivergent Mannich Reaction of Ketones with Benzoxazinones
성과년도
2018
성과 고유번호
JNL-2018-00110108861
학술지명
ADVANCED SYNTHESIS & CATALYSIS
ISSN
1615-4150
The role of lactose carrier on the powder behavior and aerodynamic performance of bosentan microparticles for dry powder inhalation
성과년도
2018
성과 고유번호
JNL-2018-00110107841
학술지명
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
ISSN
0928-0987
Long-term Survival after Repeated Local Therapy and Salvage Chemotherapy for Recurrent Metastases from Gastric Cancer: a Case Report and Literature Review
성과년도
2018
성과 고유번호
JNL-2018-00110159072
학술지명
JOURNAL OF GASTRIC CANCER
ISSN
2093-582x
Sleep-Aids Derived from Natural Products
성과년도
2018
성과 고유번호
JNL-2018-00110160252
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148
Feasibility and accessibility of electronic patient-reported outcome measures using a smartphone during routine chemotherapy: a pilot study
성과년도
2018
성과 고유번호
JNL-2018-00110155302
학술지명
SUPPORTIVE CARE IN CANCER
ISSN
0941-4355
N-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity
성과년도
2018
성과 고유번호
JNL-2018-00110104217
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Rapid, Operationally Simple, and Metal-free NBS Mediated One-pot Synthesis of 1,2-Naphthoquinone from 2-Naphthol
성과년도
2018
성과 고유번호
JNL-2018-00110108113
학술지명
ADVANCED SYNTHESIS & CATALYSIS
ISSN
1615-4150
Modulation of store-operated calcium entry and nascent adhesion by p21-activated kinase 1
성과년도
2018
성과 고유번호
JNL-2018-00110115543
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice
성과년도
2018
성과 고유번호
JNL-2018-00110116685
학술지명
INTERNATIONAL JOURNAL OF CANCER
ISSN
0020-7136
Dysregulation of 5-hydroxytryptamine 6 receptor accelerates maturation of bone-resorbing osteoclasts and induces bone loss
성과년도
2018
성과 고유번호
JNL-2018-00110116643
학술지명
THERANOSTICS
ISSN
1838-7640
Toll-Like Receptor-7 Signaling Promotes Nonalcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice
성과년도
2018
성과 고유번호
JNL-2018-00110115769
학술지명
AMERICAN JOURNAL OF PATHOLOGY
ISSN
0002-9440
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity
성과년도
2018
성과 고유번호
JNL-2018-00110117437
학술지명
SCIENTIFIC REPORTS
ISSN
2045-2322
Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice
성과년도
2018
성과 고유번호
JNL-2018-00110116991
학술지명
THERANOSTICS
ISSN
1838-7640
Estrogen deficiency exacerbates A beta-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-kappa B activation in ovariectomized mice
성과년도
2018
성과 고유번호
JNL-2018-00110116573
학술지명
BRAIN BEHAVIOR AND IMMUNITY
ISSN
0889-1591
Peptide nucleic acid (PNA) probe-based analysis to detect filaggrin mutations in atopic dermatitis patients
성과년도
2018
성과 고유번호
JNL-2018-00110117359
학술지명
EXPERIMENTAL DERMATOLOGY
ISSN
0906-6705
Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1
성과년도
2018
성과 고유번호
JNL-2018-00110117419
학술지명
THERANOSTICS
ISSN
1838-7640
Anti-inflammatory effect of Centella asiatica phytosome in a mouse model of phthalic anhydride-induced atopic dermatitis
성과년도
2018
성과 고유번호
JNL-2018-00110115645
학술지명
PHYTOMEDICINE
ISSN
0944-7113
Inhibition of skin carcinogenesis by suppression of NF-kappa B dependent ITGAV and TIMP-1 expression in IL-32 gamma overexpressed condition
성과년도
2018
성과 고유번호
JNL-2018-00110116707
학술지명
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
ISSN
1756-9966
IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation
성과년도
2018
성과 고유번호
JNL-2018-00110115765
학술지명
CELL DEATH & DISEASE
ISSN
2041-4889
K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-kappa B-mediated CHI3L1 expression
성과년도
2018
성과 고유번호
JNL-2018-00110117439
학술지명
JOURNAL OF NEUROINFLAMMATION
ISSN
1742-2094
Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination
성과년도
2018
성과 고유번호
JNL-2018-00110116973
학술지명
CANCER LETTERS
ISSN
0304-3835
Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
성과년도
2018
성과 고유번호
JNL-2018-00110116993
학술지명
IMMUNE NETWORK
ISSN
1598-2629
Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
성과년도
2018
성과 고유번호
JNL-2018-00110116145
학술지명
NEUROMOLECULAR MEDICINE
ISSN
1535-1084
A novel tubulin inhibitor STK899704 induces tumor regression in DMBA/TPA-induced skin carcinogenesis model
성과년도
2018
성과 고유번호
JNL-2018-00110117237
학술지명
EXPERIMENTAL DERMATOLOGY
ISSN
0906-6705
Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents
성과년도
2018
성과 고유번호
JNL-2018-0019685471
학술지명
BIOORGANIC CHEMISTRY
ISSN
0045-2068
Feasibility and accessibility of electronic patient-reported outcome measures using a smartphone during routine chemotherapy: a pilot study
성과년도
2018
성과 고유번호
JNL-2018-00110155302
학술지명
SUPPORTIVE CARE IN CANCER
ISSN
0941-4355
Design, synthesis and evaluation of novel N-hydroxybenzamides/N-hydroxypropenamides incorporating quinazolin-4(3H)-ones as histone deacetylase inhibitors and antitumor agents
성과년도
2018
성과 고유번호
JNL-2018-0019685471
학술지명
BIOORGANIC CHEMISTRY
ISSN
0045-2068
Novel Hydroxamic Acids Incorporating 1-((1H-1,2,3-Triazol-4-yl)methyl)-3-substituted-2-oxoindolines: Synthesis, Biological Evaluation and SAR Analysis
성과년도
2018
성과 고유번호
JNL-2018-00110101875
학술지명
MEDICINAL CHEMISTRY
ISSN
1573-4064
Dysregulation of 5-hydroxytryptamine 6 receptor accelerates maturation of bone-resorbing osteoclasts and induces bone loss
성과년도
2018
성과 고유번호
JNL-2018-00110116643
학술지명
THERANOSTICS
ISSN
1838-7640
Organocatalytic and Regiodivergent Mannich Reaction of Ketones with Benzoxazinones
성과년도
2018
성과 고유번호
JNL-2018-00110108861
학술지명
ADVANCED SYNTHESIS & CATALYSIS
ISSN
1615-4150
CXCR3-deficient mesenchymal stem cells fail to infiltrate into the nephritic kidney and do not ameliorate lupus symptoms in MRL.Fas(lpr) mice
성과년도
2018
성과 고유번호
JNL-2018-00110101367
학술지명
LUPUS
ISSN
0961-2033
Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/II alpha inhibitors
성과년도
2018
성과 고유번호
JNL-2018-00110107859
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY
ISSN
0968-0896
Toll-Like Receptor-7 Signaling Promotes Nonalcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice
성과년도
2018
성과 고유번호
JNL-2018-00110115769
학술지명
AMERICAN JOURNAL OF PATHOLOGY
ISSN
0002-9440
Dimeric- and trimeric sesquiterpenes from the flower of Inula japonica
성과년도
2018
성과 고유번호
JNL-2018-00110104263
학술지명
PHYTOCHEMISTRY
ISSN
0031-9422
Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1
성과년도
2018
성과 고유번호
JNL-2018-00110117419
학술지명
THERANOSTICS
ISSN
1838-7640
Estrogen deficiency exacerbates A beta-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-kappa B activation in ovariectomized mice
성과년도
2018
성과 고유번호
JNL-2018-00110116573
학술지명
BRAIN BEHAVIOR AND IMMUNITY
ISSN
0889-1591
CXCR3-deficient natural killer cells fail to migrate to B16F10 melanoma cells
성과년도
2018
성과 고유번호
JNL-2018-00110102805
학술지명
INTERNATIONAL IMMUNOPHARMACOLOGY
ISSN
1567-5769
Lathyrane-Type Diterpenoids from the Seeds of Euphorbia lathyris L. with Inhibitory Effects on NO Production in RAW 264.7 Cells
성과년도
2018
성과 고유번호
JNL-2018-00110107111
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations
성과년도
2018
성과 고유번호
JNL-2018-00110116993
학술지명
IMMUNE NETWORK
ISSN
1598-2629
Astaxanthin alleviated ethanol-induced liver injury by inhibition of oxidative stress and inflammatory responses via blocking of STAT3 activity
성과년도
2018
성과 고유번호
JNL-2018-00110117437
학술지명
SCIENTIFIC REPORTS
ISSN
2045-2322
Metal-free approach for the L-proline mediated synthesis of nitrones from nitrosobenzene
성과년도
2018
성과 고유번호
JNL-2018-00110108327
학술지명
TETRAHEDRON
ISSN
0040-4020
Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
성과년도
2018
성과 고유번호
JNL-2018-00110116145
학술지명
NEUROMOLECULAR MEDICINE
ISSN
1535-1084
Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination
성과년도
2018
성과 고유번호
JNL-2018-00110116973
학술지명
CANCER LETTERS
ISSN
0304-3835
Identification of antioxidant constituents of the aerial part of Plantago asiatica using LC-MS/MS coupled DPPH assay
성과년도
2018
성과 고유번호
JNL-2018-00110107843
학술지명
PHYTOCHEMISTRY LETTERS
ISSN
1874-3900
Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Fas(lPr) Mice
성과년도
2018
성과 고유번호
JNL-2018-00110101877
학술지명
STEM CELLS INTERNATIONAL
ISSN
1687-966X
Long-term Survival after Repeated Local Therapy and Salvage Chemotherapy for Recurrent Metastases from Gastric Cancer: a Case Report and Literature Review
성과년도
2018
성과 고유번호
JNL-2018-00110159072
학술지명
JOURNAL OF GASTRIC CANCER
ISSN
2093-582x
Transition-metal-free, atom-economical cascade synthesis of novel 2-sulfonated-benzo[f][1,7]naphthyridines and their cytotoxic activities
성과년도
2018
성과 고유번호
JNL-2018-00110107053
학술지명
TETRAHEDRON
ISSN
0040-4020
Nitric oxide inhibitory constituents from Siegesbeckia pubescens
성과년도
2018
성과 고유번호
JNL-2018-00110101363
학술지명
BIOORGANIC CHEMISTRY
ISSN
0045-2068
Peptide nucleic acid (PNA) probe-based analysis to detect filaggrin mutations in atopic dermatitis patients
성과년도
2018
성과 고유번호
JNL-2018-00110117359
학술지명
EXPERIMENTAL DERMATOLOGY
ISSN
0906-6705
N-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity
성과년도
2018
성과 고유번호
JNL-2018-00110104217
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-kappa B-mediated CHI3L1 expression
성과년도
2018
성과 고유번호
JNL-2018-00110117439
학술지명
JOURNAL OF NEUROINFLAMMATION
ISSN
1742-2094
Phenolic amides from Tribulus terrestris and their inhibitory effects on nitric oxide production in RAW 264.7 cells
성과년도
2018
성과 고유번호
JNL-2018-00110101365
학술지명
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269
A novel tubulin inhibitor STK899704 induces tumor regression in DMBA/TPA-induced skin carcinogenesis model
성과년도
2018
성과 고유번호
JNL-2018-00110117237
학술지명
EXPERIMENTAL DERMATOLOGY
ISSN
0906-6705
IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation
성과년도
2018
성과 고유번호
JNL-2018-00110115765
학술지명
CELL DEATH & DISEASE
ISSN
2041-4889
Inhibition of skin carcinogenesis by suppression of NF-kappa B dependent ITGAV and TIMP-1 expression in IL-32 gamma overexpressed condition
성과년도
2018
성과 고유번호
JNL-2018-00110116707
학술지명
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
ISSN
1756-9966
Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice
성과년도
2018
성과 고유번호
JNL-2018-00110116991
학술지명
THERANOSTICS
ISSN
1838-7640
Quinazoline-Based Hydroxamic Acids: Design, Synthesis, and Evaluation of Histone Deacetylase Inhibitory Effects and Cytotoxicity
성과년도
2018
성과 고유번호
JNL-2018-00110104265
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Sleep-Aids Derived from Natural Products
성과년도
2018
성과 고유번호
JNL-2018-00110160252
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148