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출원등록명	신규 인돌 유도체, 이의 제조방법, 및 이를 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약학적 조성물
산업재산권 구분	특허	특허구분	출원
출원등록번호	10-2018-0136227	출원등록자	성균관대학교 산학협력단
출원등록국가	대한민국	IPC 코드	C07D 403/04,A61K 31/506,A61P 3/10
성과년도	2018	NTIS 성과고유번호	PTR-2018-0029959900

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관련 과제(1) 관련 논문(31) 관련 장비(0) 관련 보고서(0)


레이트스테이지 약물 최적화 연구실(Late-stage Drug Optimization Laboratory) 과제년도 2018 과제번호 1711065994 연구기관 성균관대학교(자연과학캠퍼스) 연구기간 2018-03-01~2019-02-28


Novel therapeutic roles of MC-4 in combination with everolimus against advanced renal cell carcinoma by dual targeting of Akt/pyruvate kinase muscle isozyme M2 and mechanistic target of rapamycin comp... 성과년도 2018 성과 고유번호 JNL-2018-0019963974 학술지명 CANCER MEDICINE ISSN 2045-7634
Synthesis of TMPA Derivatives through Sequential Ir(III)-Catalyzed C-H Alkylation and Their Antidiabetic Evaluation 성과년도 2018 성과 고유번호 JNL-2018-0019964196 학술지명 ACS OMEGA ISSN 2470-1343
Reductive C2-Alkylation of Pyridine and Quinoline N-Oxides Using Wittig Reagents 성과년도 2018 성과 고유번호 JNL-2018-0019958820 학술지명 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ISSN 1433-7851
Direct Synthesis of 2-Acyl Acridines Using Aldimines and Anthranils: Evaluation of Cytotoxicity and Anti-Inflammatory Activity 성과년도 2018 성과 고유번호 JNL-2018-0019959586 학술지명 ASIAN JOURNAL OF ORGANIC CHEMISTRY ISSN 2193-5807
Synthesis of (2H)-Indazoles through Rh(III)-Catalyzed Annulation Reaction of Azobenzenes with Sulfoxonium Ylides 성과년도 2018 성과 고유번호 JNL-2018-0019958144 학술지명 JOURNAL OF ORGANIC CHEMISTRY ISSN 0022-3263
Novel SIRT1 inhibitor 15-deoxy-Delta(12,14)-prostaglandin J(2) and its derivatives exhibit anticancer activity through apoptotic or autophagic cell death pathways in SKOV3 cells 성과년도 2018 성과 고유번호 JNL-2018-0019963748 학술지명 INTERNATIONAL JOURNAL OF ONCOLOGY ISSN 1019-6439
Ru(II)-Catalyzed C-H Aminocarbonylation of N-(Hetero)aryl-7-azaindoles with Isocyanates 성과년도 2018 성과 고유번호 JNL-2018-0019958002 학술지명 JOURNAL OF ORGANIC CHEMISTRY ISSN 0022-3263
Reactivity of Morita-Baylis-Hillman Adducts in C-H Functionalization of (Hetero)aryl Nitrones: Access to Bridged Cycles and Carbazoles 성과년도 2018 성과 고유번호 JNL-2018-0019959020 학술지명 ORGANIC LETTERS ISSN 1523-7060
Dual Role of Anthranils as Amination and Transient Directing Group Sources: Synthesis of 2-Acyl Acridines 성과년도 2018 성과 고유번호 JNL-2018-0019958660 학술지명 ORGANIC LETTERS ISSN 1523-7060
Site-selective C-H nitration of N-aryl-7-azaindoles under palladium(II) catalysis 성과년도 2018 성과 고유번호 JNL-2018-0019959800 학술지명 TETRAHEDRON LETTERS ISSN 0040-4039
One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N-O bond cleavage 성과년도 2018 성과 고유번호 JNL-2018-0019959802 학술지명 ORGANIC CHEMISTRY FRONTIERS ISSN 2052-4129
Disparate Downstream Reactions Mediated by an lonically Controlled Supramolecular Tristate Switch 성과년도 2018 성과 고유번호 JNL-2018-0019958662 학술지명 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ISSN 0002-7863
Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells 성과년도 2018 성과 고유번호 JNL-2018-0019959762 학술지명 PHYTOMEDICINE ISSN 0944-7113
A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation 성과년도 2018 성과 고유번호 JNL-2018-0019959756 학술지명 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ISSN 1422-0067
Recent advances in N-heterocycles synthesis through catalytic C-H functionalization of azobenzenes 성과년도 2018 성과 고유번호 JNL-2018-0019959764 학술지명 TETRAHEDRON ISSN 0040-4020
Synthesis of 2-Benzazepines from Benzylamines and MBH Adducts Under Rhodium(III) Catalysis via C(sp(2))-H Functionalization 성과년도 2018 성과 고유번호 JNL-2018-0019644959 학술지명 ACS CATALYSIS ISSN 2155-5435
Novel SIRT1 inhibitor 15-deoxy-Delta(12,14)-prostaglandin J(2) and its derivatives exhibit anticancer activity through apoptotic or autophagic cell death pathways in SKOV3 cells 성과년도 2018 성과 고유번호 JNL-2018-0019963748 학술지명 INTERNATIONAL JOURNAL OF ONCOLOGY ISSN 1019-6439
Recent advances in N-heterocycles synthesis through catalytic C-H functionalization of azobenzenes 성과년도 2018 성과 고유번호 JNL-2018-0019959764 학술지명 TETRAHEDRON ISSN 0040-4020
One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N-O bond cleavage 성과년도 2018 성과 고유번호 JNL-2018-0019959802 학술지명 ORGANIC CHEMISTRY FRONTIERS ISSN 2052-4129
Site-selective C-H nitration of N-aryl-7-azaindoles under palladium(II) catalysis 성과년도 2018 성과 고유번호 JNL-2018-0019959800 학술지명 TETRAHEDRON LETTERS ISSN 0040-4039
Reactivity of Morita-Baylis-Hillman Adducts in C-H Functionalization of (Hetero)aryl Nitrones: Access to Bridged Cycles and Carbazoles 성과년도 2018 성과 고유번호 JNL-2018-0019959020 학술지명 ORGANIC LETTERS ISSN 1523-7060
Direct Synthesis of 2-Acyl Acridines Using Aldimines and Anthranils: Evaluation of Cytotoxicity and Anti-Inflammatory Activity 성과년도 2018 성과 고유번호 JNL-2018-0019959586 학술지명 ASIAN JOURNAL OF ORGANIC CHEMISTRY ISSN 2193-5807
Reductive C2-Alkylation of Pyridine and Quinoline N-Oxides Using Wittig Reagents 성과년도 2018 성과 고유번호 JNL-2018-0019958820 학술지명 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ISSN 1433-7851
Disparate Downstream Reactions Mediated by an lonically Controlled Supramolecular Tristate Switch 성과년도 2018 성과 고유번호 JNL-2018-0019958662 학술지명 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ISSN 0002-7863
Dual Role of Anthranils as Amination and Transient Directing Group Sources: Synthesis of 2-Acyl Acridines 성과년도 2018 성과 고유번호 JNL-2018-0019958660 학술지명 ORGANIC LETTERS ISSN 1523-7060
Synthesis of (2H)-Indazoles through Rh(III)-Catalyzed Annulation Reaction of Azobenzenes with Sulfoxonium Ylides 성과년도 2018 성과 고유번호 JNL-2018-0019958144 학술지명 JOURNAL OF ORGANIC CHEMISTRY ISSN 0022-3263
A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation 성과년도 2018 성과 고유번호 JNL-2018-0019959756 학술지명 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ISSN 1422-0067
Synthesis of TMPA Derivatives through Sequential Ir(III)-Catalyzed C-H Alkylation and Their Antidiabetic Evaluation 성과년도 2018 성과 고유번호 JNL-2018-0019964196 학술지명 ACS OMEGA ISSN 2470-1343
Synthesis of 2-Benzazepines from Benzylamines and MBH Adducts Under Rhodium(III) Catalysis via C(sp(2))-H Functionalization 성과년도 2018 성과 고유번호 JNL-2018-0019644959 학술지명 ACS CATALYSIS ISSN 2155-5435
Novel therapeutic roles of MC-4 in combination with everolimus against advanced renal cell carcinoma by dual targeting of Akt/pyruvate kinase muscle isozyme M2 and mechanistic target of rapamycin complex 1 pathways 성과년도 2018 성과 고유번호 JNL-2018-0019963974 학술지명 CANCER MEDICINE ISSN 2045-7634
Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells 성과년도 2018 성과 고유번호 JNL-2018-0019959762 학술지명 PHYTOMEDICINE ISSN 0944-7113


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