국가 R&D 과제 조회
과제고유번호 1711071745 당해연도 연구기간 2018-04-01 ~ 2019-02-28
과제년도 2018 총 연구기간 2016-06-01 ~ 2019-05-31
주관부처명 과학기술정보통신부 연구기관명 계명대학교
사업명 개인기초연구(과기정통부)(R&D)
과제명 한글 Lysosome을 표적을 통한 새로운 항암전략 기전 연구
영문 Mechanism study for novel anti-tumor therapeutic strategy via Lysosome targeting
연구개발단계 기초연구 지역 대구
6T분류 BT • 기초/기반기술 • 생명현상 및 기능연구
과학기술표준분류 분자세포생물학 / 세포분화/사멸

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 137,500,000 0 137,500,000
관련 논문(18) 관련 특허(0) 관련 장비(0) 관련 보고서(0)

BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
성과년도
2018
성과 고유번호
JNL-2018-00110256264
학술지명
CELL DEATH DISCOVERY
ISSN
2058-7716
Maritoclax Enhances TRAIL-Induced Apoptosis via CHOP-Mediated Upregulation of DR5 and miR-708-Mediated Downregulation of cFLIP
성과년도
2018
성과 고유번호
JNL-2018-00110131337
학술지명
MOLECULES
ISSN
1420-3049
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-induced apoptosis through upregulation of Bim expression
성과년도
2018
성과 고유번호
JNL-2018-00110131333
학술지명
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ISSN
0006-291X
HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis
성과년도
2018
성과 고유번호
JNL-2018-00110131377
학술지명
MOLECULES
ISSN
1420-3049
mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
성과년도
2018
성과 고유번호
JNL-2018-00110030344
학술지명
ONCOGENE
ISSN
0950-9232
Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells
성과년도
2018
성과 고유번호
JNL-2018-00110128681
학술지명
MOLECULES
ISSN
1420-3049
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress
성과년도
2018
성과 고유번호
JNL-2018-00110128679
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells
성과년도
2018
성과 고유번호
JNL-2018-00110128377
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression
성과년도
2018
성과 고유번호
JNL-2018-00110130251
학술지명
MOLECULES
ISSN
1420-3049
암 치료 표적으로써 cathepsin S
성과년도
2018
성과 고유번호
JNL-2018-00110119139
학술지명
생명과학회지
ISSN
1225-9918
BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
성과년도
2018
성과 고유번호
JNL-2018-00110256264
학술지명
CELL DEATH DISCOVERY
ISSN
2058-7716
Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells
성과년도
2018
성과 고유번호
JNL-2018-00110128377
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Maritoclax Enhances TRAIL-Induced Apoptosis via CHOP-Mediated Upregulation of DR5 and miR-708-Mediated Downregulation of cFLIP
성과년도
2018
성과 고유번호
JNL-2018-00110131337
학술지명
MOLECULES
ISSN
1420-3049
HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis
성과년도
2018
성과 고유번호
JNL-2018-00110131377
학술지명
MOLECULES
ISSN
1420-3049
mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
성과년도
2018
성과 고유번호
JNL-2018-00110030344
학술지명
ONCOGENE
ISSN
0950-9232
Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression
성과년도
2018
성과 고유번호
JNL-2018-00110130251
학술지명
MOLECULES
ISSN
1420-3049
Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells
성과년도
2018
성과 고유번호
JNL-2018-00110128681
학술지명
MOLECULES
ISSN
1420-3049
Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress
성과년도
2018
성과 고유번호
JNL-2018-00110128679
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613