국가 R&D 과제 조회
과제고유번호 1711072456 당해연도 연구기간 2018-04-01 ~ 2019-02-28
과제년도 2018 총 연구기간 2016-06-01 ~ 2019-05-31
주관부처명 과학기술정보통신부 연구기관명 분당서울대학교병원
사업명 개인기초연구(과기정통부)(R&D)
과제명 한글 프로텍틴DX의 투여를 통한 비알코올성 지방간질환의 새로운 치료법 개발
영문 Development of novel treatment for non-alcoholic fatty liver disease (NAFLD) through protectin DX treatment
연구개발단계 기초연구 지역 경기
6T분류 BT • 보건의료관련응용 • 의과학·의공학기술
과학기술표준분류 의약품/의약품개발기술 / 저분자의약품

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 47,015,000 0 47,015,000
관련 논문(21) 관련 특허(1) 관련 장비(0) 관련 보고서(0)

Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NF-kappa B pathway
성과년도
2018
성과 고유번호
JNL-2018-00110029334
학술지명
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
ISSN
0193-1849
Protectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 Expression
성과년도
2018
성과 고유번호
JNL-2018-00110029332
학술지명
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
ISSN
0022-3565
BAIBA Attenuates the Expression of Inflammatory Cytokines and Attachment Molecules and ER Stress in HUVECs and THP-1 Cells
성과년도
2018
성과 고유번호
JNL-2018-00110031134
학술지명
PATHOBIOLOGY
ISSN
1015-2008
Fibronectin Type III Domain Containing 4 attenuates hyperlipidemia-induced insulin resistance via suppression of inflammation and ER stress through HO-1 expression in adipocytes
성과년도
2018
성과 고유번호
JNL-2018-00110029144
학술지명
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ISSN
0006-291X
Maresin 1 attenuates pro-inflammatory reactions and ER stress in HUVECs via PPAR alpha-mediated pathway
성과년도
2018
성과 고유번호
JNL-2018-00110029454
학술지명
MOLECULAR AND CELLULAR BIOCHEMISTRY
ISSN
0300-8177
METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPAR delta-dependent pathways in skeletal muscle of mice
성과년도
2018
성과 고유번호
JNL-2018-00110030566
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
LECT2 promotes inflammation and insulin resistance in adipocytes via P38 pathways
성과년도
2018
성과 고유번호
JNL-2018-00110029046
학술지명
JOURNAL OF MOLECULAR ENDOCRINOLOGY
ISSN
0952-5041
beta-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway
성과년도
2018
성과 고유번호
JNL-2018-00110030522
학술지명
JOURNAL OF BIOMEDICAL SCIENCE
ISSN
1021-7770
Euodia daniellii Hemsl. (Bee-Bee Tree) Oil Attenuates Palmitate-Induced Lipid Accumulation and Apoptosis in Hepatocytes
성과년도
2018
성과 고유번호
JNL-2018-00110030794
학술지명
PHARMACOLOGY
ISSN
0031-7012
Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle
성과년도
2018
성과 고유번호
JNL-2018-00110031618
학술지명
MOLECULAR AND CELLULAR ENDOCRINOLOGY
ISSN
0303-7207
WISP1 promotes non-alcoholic fatty liver disease and skeletal muscle insulin resistance via TLR4/JNK signaling
성과년도
2018
성과 고유번호
JNL-2018-0019650612
학술지명
JOURNAL OF CELLULAR PHYSIOLOGY
ISSN
0021-9541
Phosphatidylcholine Causes Lipolysis and Apoptosis in Adipocytes through the Tumor Necrosis Factor Alpha-Dependent Pathway
성과년도
2018
성과 고유번호
JNL-2018-0019685455
학술지명
PHARMACOLOGY
ISSN
0031-7012
beta-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway
성과년도
2018
성과 고유번호
JNL-2018-00110030522
학술지명
JOURNAL OF BIOMEDICAL SCIENCE
ISSN
1021-7770
Fibronectin Type III Domain Containing 4 attenuates hyperlipidemia-induced insulin resistance via suppression of inflammation and ER stress through HO-1 expression in adipocytes
성과년도
2018
성과 고유번호
JNL-2018-00110029144
학술지명
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ISSN
0006-291X
METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPAR delta-dependent pathways in skeletal muscle of mice
성과년도
2018
성과 고유번호
JNL-2018-00110030566
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle
성과년도
2018
성과 고유번호
JNL-2018-00110031618
학술지명
MOLECULAR AND CELLULAR ENDOCRINOLOGY
ISSN
0303-7207
Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NF-kappa B pathway
성과년도
2018
성과 고유번호
JNL-2018-00110029334
학술지명
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
ISSN
0193-1849
Maresin 1 attenuates pro-inflammatory reactions and ER stress in HUVECs via PPAR alpha-mediated pathway
성과년도
2018
성과 고유번호
JNL-2018-00110029454
학술지명
MOLECULAR AND CELLULAR BIOCHEMISTRY
ISSN
0300-8177
LECT2 promotes inflammation and insulin resistance in adipocytes via P38 pathways
성과년도
2018
성과 고유번호
JNL-2018-00110029046
학술지명
JOURNAL OF MOLECULAR ENDOCRINOLOGY
ISSN
0952-5041
Phosphatidylcholine Causes Lipolysis and Apoptosis in Adipocytes through the Tumor Necrosis Factor Alpha-Dependent Pathway
성과년도
2018
성과 고유번호
JNL-2018-0019685455
학술지명
PHARMACOLOGY
ISSN
0031-7012
BAIBA Attenuates the Expression of Inflammatory Cytokines and Attachment Molecules and ER Stress in HUVECs and THP-1 Cells
성과년도
2018
성과 고유번호
JNL-2018-00110031134
학술지명
PATHOBIOLOGY
ISSN
1015-2008