국가 R&D 과제 조회
과제고유번호 1711064828 당해연도 연구기간 2018-02-01 ~ 2018-12-31
과제년도 2018 총 연구기간 2016-07-01 ~ 2021-03-31
주관부처명 과학기술정보통신부 연구기관명 한국과학기술연구원
사업명 뇌과학원천기술개발(R&D)
과제명 한글 혈액-뇌장벽 손상 측정/제어 및 뇌단백질 변형/응집체 분석을 위한 코어 기술 개발
영문 Development of core technologies for measurement/control of blood-brain barrier damage and analysis of neuroprotein modification/aggregation
연구개발단계 기초연구 지역 서울
6T분류 BT • 보건의료관련응용 • 난치성 질환치료기술
과학기술표준분류 뇌의약 / 만성퇴행성 뇌질환

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 917,000,000 0 917,000,000
관련 논문(29) 관련 특허(4) 관련 장비(0) 관련 보고서(0)

Metal Ion Effects on A and Tau Aggregation
성과년도
2018
성과 고유번호
JNL-2018-0019913549
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Glioblastoma-secreted soluble CD44 activates tau pathology in the brain
성과년도
2018
성과 고유번호
JNL-2018-0019913545
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
Effect of Topographical Feature Size on the Trend of Cell Behaviors
성과년도
2018
성과 고유번호
JNL-2018-0019913547
학술지명
IEEE TRANSACTIONS ON NANOTECHNOLOGY
ISSN
1536-125X
Enzyme-loaded paper combined impedimetric sensor for the determination of the low-level of cholesterol in saliva
성과년도
2018
성과 고유번호
JNL-2018-0019913523
학술지명
SENSORS AND ACTUATORS B-CHEMICAL
ISSN
0925-4005
Hydrogel micropost-based qPCR for multiplex detection of miRNAs associated with Alzheimer's disease
성과년도
2018
성과 고유번호
JNL-2018-0019913499
학술지명
BIOSENSORS & BIOELECTRONICS
ISSN
0956-5663
Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions
성과년도
2018
성과 고유번호
JNL-2018-0019913495
학술지명
GERONTOLOGY
ISSN
0304-324X
Visualization of Tau-Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique
성과년도
2018
성과 고유번호
JNL-2018-0019913525
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Development of tau PET Imaging Ligands and their Utility in Preclinical and Clinical Studies
성과년도
2018
성과 고유번호
JNL-2018-0019913493
학술지명
Nuclear Medicine and Molecular Imaging
ISSN
1869-3474
Functional significance of O-GlcNAc modification in regulating neuronal properties
성과년도
2018
성과 고유번호
JNL-2018-0019913485
학술지명
PHARMACOLOGICAL RESEARCH
ISSN
1043-6618
Dual Function of USP14 Deubiquitinase in Cellular Proteasomal Activity and Autophagic Flux
성과년도
2018
성과 고유번호
JNL-2018-0019913457
학술지명
CELL REPORTS
ISSN
2211-1247
Supramolecular Modulation of Structural Polymorphism in Pathogenic -Synuclein Fibrils Using Copper(II) Coordination
성과년도
2018
성과 고유번호
JNL-2018-0019913453
학술지명
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN
1433-7851
Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly
성과년도
2018
성과 고유번호
JNL-2018-0019913143
학술지명
ALZHEIMER DISEASE & ASSOCIATED DISORDERS
ISSN
0893-0341
Inactivation of USP14 Perturbs Ubiquitin Homeostasis and Delays the Cell Cycle in Mouse Embryonic Fibroblasts and in Fruit Fly Drosophila
성과년도
2018
성과 고유번호
JNL-2018-0019913589
학술지명
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
ISSN
1015-8987
Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors
성과년도
2018
성과 고유번호
JNL-2018-0019913591
학술지명
FRONTIERS IN PHARMACOLOGY
ISSN
1663-9812
Gintonin absorption in intestinal model systems
성과년도
2018
성과 고유번호
JNL-2018-0019913153
학술지명
JOURNAL OF GINSENG RESEARCH
ISSN
1226-8453
Degradation or aggregation: the ramifications of post-translational modifications on tau
성과년도
2018
성과 고유번호
JNL-2018-0019913551
학술지명
BMB REPORTS
ISSN
1976-6696
Gintonin, a ginseng-derived exogenous lysophosphatidic acid receptor ligand, enhances blood-brain barrier permeability and brain delivery
성과년도
2018
성과 고유번호
JNL-2018-0019913553
학술지명
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN
0141-8130
Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions
성과년도
2018
성과 고유번호
JNL-2018-0019913495
학술지명
GERONTOLOGY
ISSN
0304-324X
Visualization of Tau-Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique
성과년도
2018
성과 고유번호
JNL-2018-0019913525
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Dual Function of USP14 Deubiquitinase in Cellular Proteasomal Activity and Autophagic Flux
성과년도
2018
성과 고유번호
JNL-2018-0019913457
학술지명
CELL REPORTS
ISSN
2211-1247
Enzyme-loaded paper combined impedimetric sensor for the determination of the low-level of cholesterol in saliva
성과년도
2018
성과 고유번호
JNL-2018-0019913523
학술지명
SENSORS AND ACTUATORS B-CHEMICAL
ISSN
0925-4005
Degradation or aggregation: the ramifications of post-translational modifications on tau
성과년도
2018
성과 고유번호
JNL-2018-0019913551
학술지명
BMB REPORTS
ISSN
1976-6696
Glioblastoma-secreted soluble CD44 activates tau pathology in the brain
성과년도
2018
성과 고유번호
JNL-2018-0019913545
학술지명
EXPERIMENTAL AND MOLECULAR MEDICINE
ISSN
1226-3613
Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly
성과년도
2018
성과 고유번호
JNL-2018-0019913143
학술지명
ALZHEIMER DISEASE & ASSOCIATED DISORDERS
ISSN
0893-0341
Supramolecular Modulation of Structural Polymorphism in Pathogenic -Synuclein Fibrils Using Copper(II) Coordination
성과년도
2018
성과 고유번호
JNL-2018-0019913453
학술지명
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN
1433-7851
Functional significance of O-GlcNAc modification in regulating neuronal properties
성과년도
2018
성과 고유번호
JNL-2018-0019913485
학술지명
PHARMACOLOGICAL RESEARCH
ISSN
1043-6618
Inactivation of USP14 Perturbs Ubiquitin Homeostasis and Delays the Cell Cycle in Mouse Embryonic Fibroblasts and in Fruit Fly Drosophila
성과년도
2018
성과 고유번호
JNL-2018-0019913589
학술지명
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
ISSN
1015-8987
Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors
성과년도
2018
성과 고유번호
JNL-2018-0019913591
학술지명
FRONTIERS IN PHARMACOLOGY
ISSN
1663-9812
Gintonin, a ginseng-derived exogenous lysophosphatidic acid receptor ligand, enhances blood-brain barrier permeability and brain delivery
성과년도
2018
성과 고유번호
JNL-2018-0019913553
학술지명
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN
0141-8130