국가 R&D 과제 조회
과제고유번호 1711064908 당해연도 연구기간 2018-01-01 ~ 2018-12-31
과제년도 2018 총 연구기간 2017-04-01 ~ 2020-03-31
주관부처명 과학기술정보통신부 연구기관명 순천향대학교
사업명 바이오.의료기술개발(R&D)
과제명 한글 임상적합 유효약제를 이용한 만성콩팥병 환자의 콩팥손상과 심혈관 합병증에 대한 환자 맞춤형 줄기세포 치료제 개발
영문 Development of patient-derived functional stem cell therapeutics for chronic kidney disease patients
연구개발단계 기초연구 지역 충남
6T분류 BT • 보건의료관련응용 • 생체조직 재생기술
과학기술표준분류 기타 보건의료 / 달리 분류되지 않는 보건의료

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 200,000,000 0 200,000,000
관련 논문(20) 관련 특허(1) 관련 장비(0) 관련 보고서(0)

Combination of MSC spheroids wrapped within autologous composite sheet dually protects against immune rejection and enhances stem cell transplantation efficacy
성과년도
2018
성과 고유번호
JNL-2018-0019919323
학술지명
TISSUE & CELL
ISSN
0040-8166
Administration of Cripto in GRP78 overexpressed human MSCs enhances stem cell viability and angiogenesis during human MSC transplantation therapy
성과년도
2018
성과 고유번호
JNL-2018-0019919325
학술지명
CELL PROLIFERATION
ISSN
0960-7722
Tauroursodeoxycholic Acid Protects against the Effects of P-Cresol-Induced Reactive Oxygen Species via the Expression of Cellular Prion Protein
성과년도
2018
성과 고유번호
JNL-2018-0019919375
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Pioglitazone Protects Mesenchymal Stem Cells against P-Cresol-Induced Mitochondrial Dysfunction via Up-Regulation of PINK-1
성과년도
2018
성과 고유번호
JNL-2018-0019919277
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis
성과년도
2018
성과 고유번호
JNL-2018-0019919241
학술지명
MARINE DRUGS
ISSN
1660-3397
Melatonin Promotes Apoptosis of Oxaliplatin-resistant Colorectal Cancer Cells Through Inhibition of Cellular Prion Protein
성과년도
2018
성과 고유번호
JNL-2018-0019919373
학술지명
ANTICANCER RESEARCH
ISSN
0250-7005
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis
성과년도
2018
성과 고유번호
JNL-2018-0019919377
학술지명
JOURNAL OF PINEAL RESEARCH
ISSN
0742-3098
C-Met-Activated Mesenchymal Stem Cells Rescue Ischemic Damage via Interaction with Cellular Prion Protein
성과년도
2018
성과 고유번호
JNL-2018-0019919379
학술지명
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
ISSN
1015-8987
Melatonin Promotes Apoptosis of Colorectal Cancer Cells via Superoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression
성과년도
2018
성과 고유번호
JNL-2018-0019919095
학술지명
ANTICANCER RESEARCH
ISSN
0250-7005
Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion...
성과년도
2018
성과 고유번호
JNL-2018-0019919155
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy
성과년도
2018
성과 고유번호
JNL-2018-0019867236
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148
Melatonin Promotes Apoptosis of Colorectal Cancer Cells via Superoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression
성과년도
2018
성과 고유번호
JNL-2018-0019919095
학술지명
ANTICANCER RESEARCH
ISSN
0250-7005
Pioglitazone Protects Mesenchymal Stem Cells against P-Cresol-Induced Mitochondrial Dysfunction via Up-Regulation of PINK-1
성과년도
2018
성과 고유번호
JNL-2018-0019919277
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis
성과년도
2018
성과 고유번호
JNL-2018-0019919377
학술지명
JOURNAL OF PINEAL RESEARCH
ISSN
0742-3098
Combination of MSC spheroids wrapped within autologous composite sheet dually protects against immune rejection and enhances stem cell transplantation efficacy
성과년도
2018
성과 고유번호
JNL-2018-0019919323
학술지명
TISSUE & CELL
ISSN
0040-8166
Melatonin Promotes Apoptosis of Oxaliplatin-resistant Colorectal Cancer Cells Through Inhibition of Cellular Prion Protein
성과년도
2018
성과 고유번호
JNL-2018-0019919373
학술지명
ANTICANCER RESEARCH
ISSN
0250-7005
Tauroursodeoxycholic Acid Protects against the Effects of P-Cresol-Induced Reactive Oxygen Species via the Expression of Cellular Prion Protein
성과년도
2018
성과 고유번호
JNL-2018-0019919375
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression
성과년도
2018
성과 고유번호
JNL-2018-0019919155
학술지명
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN
1422-0067
Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy
성과년도
2018
성과 고유번호
JNL-2018-0019867236
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148
Administration of Cripto in GRP78 overexpressed human MSCs enhances stem cell viability and angiogenesis during human MSC transplantation therapy
성과년도
2018
성과 고유번호
JNL-2018-0019919325
학술지명
CELL PROLIFERATION
ISSN
0960-7722