국가 R&D 과제 조회
과제고유번호 1711075837 당해연도 연구기간 2018-07-01 ~ 2019-04-30
과제년도 2018 총 연구기간 2010-09-01 ~ 2019-08-31
주관부처명 과학기술정보통신부 연구기관명 성균관대학교(자연과학캠퍼스)
사업명 집단연구지원(R&D)
과제명 한글 에피지놈 제어 연구센터
영문 Research Center for Epigenome Regulation
연구개발단계 기초연구 지역 경기
6T분류 BT • 기초/기반기술 • 생명현상 및 기능연구
과학기술표준분류 의생명과학 / 분자세포생물학

총 연구비
연도 정부 연구비(원) 민간 연구비(원) 사업예산
2018 833,000,000 0 833,000,000
관련 논문(45) 관련 특허(3) 관련 장비(0) 관련 보고서(0)

LCMS-based Analysis of Bioactive Compounds from the Bark of Betula platyphylla var. japonica and Their Effects on Regulation of Adipocyte and Osteoblast Differentiation
성과년도
2018
성과 고유번호
JNL-2018-00110428939
학술지명
Natural Product Sciences
ISSN
1226-3907
Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization
성과년도
2018
성과 고유번호
JNL-2018-00110029708
학술지명
NUCLEIC ACIDS RESEARCH
ISSN
0305-1048
Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells
성과년도
2018
성과 고유번호
JNL-2018-00110023655
학술지명
JOURNAL OF GINSENG RESEARCH
ISSN
1226-8453
Structural Characterization of Terpenoids from Abies holophylla Using Computational and Statistical Methods and Their Biological Activities
성과년도
2018
성과 고유번호
JNL-2018-00110023943
학술지명
JOURNAL OF NATURAL PRODUCTS
ISSN
0163-3864
Phytochemical Constituents of Capsella bursa-pastoris and Their Anti-inflammatory Activity
성과년도
2018
성과 고유번호
JNL-2018-00110023981
학술지명
Natural Product Sciences
ISSN
1226-3907
Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy
성과년도
2018
성과 고유번호
JNL-2018-00110024311
학술지명
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269
Rare Thioglycosides from the Roots of Wasabia japonica
성과년도
2018
성과 고유번호
JNL-2018-00110024697
학술지명
JOURNAL OF NATURAL PRODUCTS
ISSN
0163-3864
BST106 Protects against Cartilage Damage by Inhibition of Apoptosis and Enhancement of Autophagy in Osteoarthritic Rats
성과년도
2018
성과 고유번호
JNL-2018-00110024239
학술지명
BIOLOGICAL & PHARMACEUTICAL BULLETIN
ISSN
0918-6158
Eudesmin impairs adipogenic differentiation via inhibition of S6K1 signaling pathway
성과년도
2018
성과 고유번호
JNL-2018-00110024715
학술지명
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ISSN
0006-291X
Determination of isoorientin levels in rat plasma after oral administration of Vaccinum bracteatum Thunb. methanol extract by high-performance liquid chromatography-tandem mass spectrometry
성과년도
2018
성과 고유번호
JNL-2018-00110024699
학술지명
BIOMEDICAL CHROMATOGRAPHY
ISSN
0269-3879
Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis
성과년도
2018
성과 고유번호
JNL-2018-00110024709
학술지명
THERANOSTICS
ISSN
1838-7640
Bioactivity-Guided Isolation of Anti-Inflammatory Constituents of the Rare Mushroom Calvatia nipponica in LPS-Stimulated RAW264.7 Macrophages
성과년도
2018
성과 고유번호
JNL-2018-00110024235
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Identification of protoberberine alkaloids as novel histone methyltransferase G9a inhibitors by structure-based virtual screening
성과년도
2018
성과 고유번호
JNL-2018-00110024501
학술지명
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
ISSN
0920-654X
The memory-enhancing effects of 7,8,4 '-trihydroxyisoflavone, a major metabolite of daidzein, are associated with activation of the cholinergic system and BDNF signaling pathway in mice
성과년도
2018
성과 고유번호
JNL-2018-00110024485
학술지명
BRAIN RESEARCH BULLETIN
ISSN
0361-9230
Biological Evaluation of a New Lignan from the Roots of Rice (Oryza sativa)
성과년도
2018
성과 고유번호
JNL-2018-00110024499
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
7 alpha, 15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs
성과년도
2018
성과 고유번호
JNL-2018-0019834864
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN
0960-894X
Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice
성과년도
2018
성과 고유번호
JNL-2018-0019834768
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148
Chemical characterization of cytotoxic indole acetic acid derivative from mulberry fruit (Morus alba L.) against human cervical cancer
성과년도
2018
성과 고유번호
JNL-2018-0019834708
학술지명
BIOORGANIC CHEMISTRY
ISSN
0045-2068
S6K1 controls epigenetic plasticity for the expression of pancreatic alpha/beta cell marker genes
성과년도
2018
성과 고유번호
JNL-2018-0019834902
학술지명
JOURNAL OF CELLULAR BIOCHEMISTRY
ISSN
0730-2312
Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells
성과년도
2018
성과 고유번호
JNL-2018-0019834832
학술지명
JOURNAL OF FUNCTIONAL FOODS
ISSN
1756-4646
A New Steroidal Glycoside from Allium macrostemon Bunge
성과년도
2018
성과 고유번호
JNL-2018-0019834830
학술지명
Natural Product Sciences
ISSN
1226-3907
6,7,4 '-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice
성과년도
2018
성과 고유번호
JNL-2018-0019834860
학술지명
EUROPEAN JOURNAL OF PHARMACOLOGY
ISSN
0014-2999
Curcuzedoalide contributes to the cytotoxicity of Curcuma zedoaria rhizomes against human gastric cancer AGS cells through induction of apoptosis
성과년도
2018
성과 고유번호
JNL-2018-0019835060
학술지명
JOURNAL OF ETHNOPHARMACOLOGY
ISSN
0378-8741
TWO NEW STEROIDAL ALKALOIDS FROM THE BULBS OF FRITILLARIA THUNBERGII
성과년도
2018
성과 고유번호
JNL-2018-0019834628
학술지명
HETEROCYCLES
ISSN
0385-5414
A NEW PHENOLIC COMPOUND FROM SALIX GLANDULOSA
성과년도
2018
성과 고유번호
JNL-2018-0019834974
학술지명
HETEROCYCLES
ISSN
0385-5414
A NEW PHENOLIC COMPOUND FROM SALIX GLANDULOSA
성과년도
2018
성과 고유번호
JNL-2018-0019834974
학술지명
HETEROCYCLES
ISSN
0385-5414
Eudesmin impairs adipogenic differentiation via inhibition of S6K1 signaling pathway
성과년도
2018
성과 고유번호
JNL-2018-00110024715
학술지명
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
ISSN
0006-291X
Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization
성과년도
2018
성과 고유번호
JNL-2018-00110029708
학술지명
NUCLEIC ACIDS RESEARCH
ISSN
0305-1048
Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis
성과년도
2018
성과 고유번호
JNL-2018-00110024709
학술지명
THERANOSTICS
ISSN
1838-7640
Rare Thioglycosides from the Roots of Wasabia japonica
성과년도
2018
성과 고유번호
JNL-2018-00110024697
학술지명
JOURNAL OF NATURAL PRODUCTS
ISSN
0163-3864
Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice
성과년도
2018
성과 고유번호
JNL-2018-0019834768
학술지명
BIOMOLECULES & THERAPEUTICS
ISSN
1976-9148
Bioactivity-Guided Isolation of Anti-Inflammatory Constituents of the Rare Mushroom Calvatia nipponica in LPS-Stimulated RAW264.7 Macrophages
성과년도
2018
성과 고유번호
JNL-2018-00110024235
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872
Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy
성과년도
2018
성과 고유번호
JNL-2018-00110024311
학술지명
ARCHIVES OF PHARMACAL RESEARCH
ISSN
0253-6269
Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells
성과년도
2018
성과 고유번호
JNL-2018-00110023655
학술지명
JOURNAL OF GINSENG RESEARCH
ISSN
1226-8453
Structural Characterization of Terpenoids from Abies holophylla Using Computational and Statistical Methods and Their Biological Activities
성과년도
2018
성과 고유번호
JNL-2018-00110023943
학술지명
JOURNAL OF NATURAL PRODUCTS
ISSN
0163-3864
S6K1 controls epigenetic plasticity for the expression of pancreatic alpha/beta cell marker genes
성과년도
2018
성과 고유번호
JNL-2018-0019834902
학술지명
JOURNAL OF CELLULAR BIOCHEMISTRY
ISSN
0730-2312
Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells
성과년도
2018
성과 고유번호
JNL-2018-0019834832
학술지명
JOURNAL OF FUNCTIONAL FOODS
ISSN
1756-4646
6,7,4 '-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice
성과년도
2018
성과 고유번호
JNL-2018-0019834860
학술지명
EUROPEAN JOURNAL OF PHARMACOLOGY
ISSN
0014-2999
TWO NEW STEROIDAL ALKALOIDS FROM THE BULBS OF FRITILLARIA THUNBERGII
성과년도
2018
성과 고유번호
JNL-2018-0019834628
학술지명
HETEROCYCLES
ISSN
0385-5414
The memory-enhancing effects of 7,8,4 '-trihydroxyisoflavone, a major metabolite of daidzein, are associated with activation of the cholinergic system and BDNF signaling pathway in mice
성과년도
2018
성과 고유번호
JNL-2018-00110024485
학술지명
BRAIN RESEARCH BULLETIN
ISSN
0361-9230
BST106 Protects against Cartilage Damage by Inhibition of Apoptosis and Enhancement of Autophagy in Osteoarthritic Rats
성과년도
2018
성과 고유번호
JNL-2018-00110024239
학술지명
BIOLOGICAL & PHARMACEUTICAL BULLETIN
ISSN
0918-6158
Identification of protoberberine alkaloids as novel histone methyltransferase G9a inhibitors by structure-based virtual screening
성과년도
2018
성과 고유번호
JNL-2018-00110024501
학술지명
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
ISSN
0920-654X
7 alpha, 15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs
성과년도
2018
성과 고유번호
JNL-2018-0019834864
학술지명
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN
0960-894X
Curcuzedoalide contributes to the cytotoxicity of Curcuma zedoaria rhizomes against human gastric cancer AGS cells through induction of apoptosis
성과년도
2018
성과 고유번호
JNL-2018-0019835060
학술지명
JOURNAL OF ETHNOPHARMACOLOGY
ISSN
0378-8741
Biological Evaluation of a New Lignan from the Roots of Rice (Oryza sativa)
성과년도
2018
성과 고유번호
JNL-2018-00110024499
학술지명
CHEMISTRY & BIODIVERSITY
ISSN
1612-1872