출원등록명	케스페이즈-1 활성 측정용 프로브, 이를 포함하는 염증성 질환 진단용 조성물
산업재산권 구분	특허	특허구분	출원
출원등록번호	10-2018-0109757	출원등록자	한국과학기술연구원;서울대학교산학협력단
출원등록국가	대한민국	IPC 코드	G01N 33/68,C12Q 1/37,G01N 21/64
성과년도	2018	NTIS 성과고유번호	PTO-2018-00210186534

맞춤형 진단·치료,재생, 재활 및 신약개발사업(Head and Neck Reconstruction, Virtual surgery, Surgical guide, Surgical work flow, Stroke, Hemiparalysis, Exercise Rehabilitation, Wearable Device, Exoskeleton, Intention Recognition, Gait Pattern, Te...) 과제년도 2018 과제번호 1711079879 연구기관 한국과학기술연구원 연구기간 2018-01-01~2018-12-31

An Implantable Wireless Neural Interface System for Simultaneous Recording and Stimulation of Peripheral Nerve with a Single Cuff Electrode 성과년도 2018 성과 고유번호 JNL-2018-00110188709 학술지명 SENSORS ISSN 1424-8220

Determination of Optimal Heart Rate Variability Features Based on SVM-Recursive Feature Elimination for Cumulative Stress Monitoring Using ECG Sensor 성과년도 2018 성과 고유번호 JNL-2018-00110188711 학술지명 SENSORS ISSN 1424-8220

Compact Optical Nerve Cuff Electrode for Simultaneous Neural Activity Monitoring and Optogenetic Stimulation of Peripheral Nerves 성과년도 2018 성과 고유번호 JNL-2018-00110188713 학술지명 SCIENTIFIC REPORTS ISSN 2045-2322

Feasibility Study on a Segmented Ferrofluid Flow Linear Generator for Increasing the Time-Varying Magnetic Flux 성과년도 2018 성과 고유번호 JNL-2018-00110188715 학술지명 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY ISSN 1533-4880

부분의치환자의 수면무호흡증 개선용 하악 전방 이동장치의 최적설계 성과년도 2018 성과 고유번호 JNL-2018-00110188717 학술지명 대한기계학회논문집 A ISSN 1226-4873

Linear Feature Projection-Based Sensory Event Detection from the Multiunit Activity of Dorsal Root Ganglion Recordings 성과년도 2018 성과 고유번호 JNL-2018-00110188707 학술지명 SENSORS ISSN 1424-8220

Double-pulse laser illumination method for measuring fast cerebral blood flow velocities in the deep brain using a fiber-bundle-based endomicroscopy system 성과년도 2018 성과 고유번호 JNL-2018-00110188710 학술지명 BIOMEDICAL OPTICS EXPRESS ISSN 2156-7085

Numerical Simulation on the Induced Voltage Across the Coil Terminal by the Segmented Flow of Ferrofluid and Air-Layer 성과년도 2018 성과 고유번호 JNL-2018-00110188714 학술지명 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY ISSN 1533-4880

BUBBLE DYNAMICS IN BOILING HISTOTRIPSY 성과년도 2018 성과 고유번호 JNL-2018-00110188706 학술지명 ULTRASOUND IN MEDICINE AND BIOLOGY ISSN 0301-5629

Graded 6-OHDA-induced dopamine depletion in the nigrostriatal pathway evokes progressive pathological neuronal activities in the subthalamic nucleus of a hemi-parkinsonian mouse 성과년도 2018 성과 고유번호 JNL-2018-00110188708 학술지명 BEHAVIOURAL BRAIN RESEARCH ISSN 0166-4328

AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development 성과년도 2018 성과 고유번호 JNL-2018-00110188702 학술지명 MOLECULAR CANCER RESEARCH ISSN 1541-7786

A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration 성과년도 2018 성과 고유번호 JNL-2018-00110188696 학술지명 STEM CELLS INTERNATIONAL ISSN 1687-966X

Direct observation of DNA target searching and cleavage by CRISPR-Cas12a 성과년도 2018 성과 고유번호 JNL-2018-00110188682 학술지명 NATURE COMMUNICATIONS ISSN 2041-1723

Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging 성과년도 2018 성과 고유번호 JNL-2018-00110188694 학술지명 DRUG DELIVERY ISSN 1071-7544

Phosphoproteomic analysis reveals PAK2 as a therapeutic target for lapatinib resistance in HER2-positive breast cancer cells 성과년도 2018 성과 고유번호 JNL-2018-00110188700 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment 성과년도 2018 성과 고유번호 JNL-2018-00110188698 학술지명 ACS NANO ISSN 1936-0851

Modulation of Cerebellar Cortical Plasticity Using Low-Intensity Focused Ultrasound for Poststroke Sensorimotor Function Recovery 성과년도 2018 성과 고유번호 JNL-2018-00110188712 학술지명 NEUROREHABILITATION AND NEURAL REPAIR ISSN 1545-9683

SEPROGADIC-serum protein-based gastric cancer prediction model for prognosis and selection of proper adjuvant therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188701 학술지명 SCIENTIFIC REPORTS ISSN 2045-2322

K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death 성과년도 2018 성과 고유번호 JNL-2018-00110188703 학술지명 ONCOGENE ISSN 0950-9232

Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway 성과년도 2018 성과 고유번호 JNL-2018-00110188704 학술지명 SCIENCE ISSN 0036-8075

Neutralizing the Detrimental Effect of an N-Hydroxysuccinimide Quenching Reagent on Phosphopeptide in Quantitative Proteomics 성과년도 2018 성과 고유번호 JNL-2018-00110188699 학술지명 ANALYTICAL CHEMISTRY ISSN 0003-2700

Iodinated Echogenic Glycol Chitosan Nanoparticles for X-ray CT/US Dual Imaging of Tumor 성과년도 2018 성과 고유번호 JNL-2018-00110188685 학술지명 Nanotheranostics ISSN 2206-7418

PLGA nanoparticles co-delivering MDR1 and BCL2 siRNA for overcoming resistance of paclitaxel and cisplatin in recurrent or advanced ovarian cancer 성과년도 2018 성과 고유번호 JNL-2018-00110188687 학술지명 SCIENTIFIC REPORTS ISSN 2045-2322

Biochemical and Structural Insights into an Fe (II)/alpha-Ketoglutarate/O-2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO) 성과년도 2018 성과 고유번호 JNL-2018-00110188686 학술지명 JOURNAL OF MOLECULAR BIOLOGY ISSN 0022-2836

PEG-PLA-Coated and Uncoated Radio-Luminescent CaWO4 Micro- and Nanoparticles for Concomitant Radiation and UV-A/Radio-Enhancement Cancer Treatments 성과년도 2018 성과 고유번호 JNL-2018-00110188692 학술지명 ACS BIOMATERIALS SCIENCE & ENGINEERING ISSN 2373-9878

Nanomaterials in Skin-Inspired Electronics: Toward Soft and Robust Skin-like Electronic Nanosystems 성과년도 2018 성과 고유번호 JNL-2018-00110188716 학술지명 ACS NANO ISSN 1936-0851

Automated detection and classification of the proximal humerus fracture by using deep learning algorithm 성과년도 2018 성과 고유번호 JNL-2018-00110188719 학술지명 ACTA ORTHOPAEDICA ISSN 1745-3674

3D computer simulation analysis of the flap volume change in total tongue reconstruction flaps 성과년도 2018 성과 고유번호 JNL-2018-00110188718 학술지명 JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY ISSN 1010-5182

Quantification of protein markers monitoring the pre-analytical effect of blood storage time before plasma isolation using N-15 metabolically labeled recombinant proteins 성과년도 2018 성과 고유번호 JNL-2018-00110188705 학술지명 JOURNAL OF MASS SPECTROMETRY ISSN 1076-5174

The ADP-ribose reactive NUDIX hydrolase isoforms can modulate HIF-1 alpha in cancer cells 성과년도 2018 성과 고유번호 JNL-2018-00110188684 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

Single-Molecule Co-Immunoprecipitation Reveals Functional Inheritance of EGFRs in Extracellular Vesicles 성과년도 2018 성과 고유번호 JNL-2018-00110188689 학술지명 SMALL ISSN 1613-6810

Nanoscale polyelectrolyte complexes encapsulating mRNA and long-chained siRNA for combinatorial cancer gene therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188693 학술지명 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY ISSN 1226-086X

Development of Biocompatible HA Hydrogels Embedded with a New Synthetic Peptide Promoting Cellular Migration for Advanced Wound Care Management 성과년도 2018 성과 고유번호 JNL-2018-00110188690 학술지명 ADVANCED SCIENCE ISSN 2198-3844

Identification of Plasma Membrane Glycoproteins Specific to Human Glioblastoma Multiforme Cells Using Lectin Arrays and LC-MS/MS 성과년도 2018 성과 고유번호 JNL-2018-00110188695 학술지명 PROTEOMICS ISSN 1615-9853

Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells 성과년도 2018 성과 고유번호 JNL-2018-00110188697 학술지명 STEM CELLS INTERNATIONAL ISSN 1687-966X

Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors 성과년도 2018 성과 고유번호 JNL-2018-00110188681 학술지명 NATURE BIOMEDICAL ENGINEERING ISSN 2157-846X

Implication of multivalent aptamers in DNA and DNA-RNA hybrid structures for efficient drug delivery in vitro and in vivo 성과년도 2018 성과 고유번호 JNL-2018-00110188691 학술지명 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY ISSN 1226-086X

Engineering nanoparticle strategies for effective cancer immunotherapy 성과년도 2018 성과 고유번호 JNL-2018-00110188683 학술지명 BIOMATERIALS ISSN 0142-9612

PEGylated DC-Chol/DOPE cationic liposomes containing KSP siRNA as a systemic siRNA delivery Carrier for ovarian cancer therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188688 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

3D computer simulation analysis of the flap volume change in total tongue reconstruction flaps 성과년도 2018 성과 고유번호 JNL-2018-00110188718 학술지명 JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY ISSN 1010-5182

Automated detection and classification of the proximal humerus fracture by using deep learning algorithm 성과년도 2018 성과 고유번호 JNL-2018-00110188719 학술지명 ACTA ORTHOPAEDICA ISSN 1745-3674

Quantification of protein markers monitoring the pre-analytical effect of blood storage time before plasma isolation using N-15 metabolically labeled recombinant proteins 성과년도 2018 성과 고유번호 JNL-2018-00110188705 학술지명 JOURNAL OF MASS SPECTROMETRY ISSN 1076-5174

Nanomaterials in Skin-Inspired Electronics: Toward Soft and Robust Skin-like Electronic Nanosystems 성과년도 2018 성과 고유번호 JNL-2018-00110188716 학술지명 ACS NANO ISSN 1936-0851

Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway 성과년도 2018 성과 고유번호 JNL-2018-00110188704 학술지명 SCIENCE ISSN 0036-8075

The ADP-ribose reactive NUDIX hydrolase isoforms can modulate HIF-1 alpha in cancer cells 성과년도 2018 성과 고유번호 JNL-2018-00110188684 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

SEPROGADIC-serum protein-based gastric cancer prediction model for prognosis and selection of proper adjuvant therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188701 학술지명 SCIENTIFIC REPORTS ISSN 2045-2322

Biochemical and Structural Insights into an Fe (II)/alpha-Ketoglutarate/O-2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO) 성과년도 2018 성과 고유번호 JNL-2018-00110188686 학술지명 JOURNAL OF MOLECULAR BIOLOGY ISSN 0022-2836

Development of Biocompatible HA Hydrogels Embedded with a New Synthetic Peptide Promoting Cellular Migration for Advanced Wound Care Management 성과년도 2018 성과 고유번호 JNL-2018-00110188690 학술지명 ADVANCED SCIENCE ISSN 2198-3844

PEGylated DC-Chol/DOPE cationic liposomes containing KSP siRNA as a systemic siRNA delivery Carrier for ovarian cancer therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188688 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

Compact Optical Nerve Cuff Electrode for Simultaneous Neural Activity Monitoring and Optogenetic Stimulation of Peripheral Nerves 성과년도 2018 성과 고유번호 JNL-2018-00110188713 학술지명 SCIENTIFIC REPORTS ISSN 2045-2322

Single-Molecule Co-Immunoprecipitation Reveals Functional Inheritance of EGFRs in Extracellular Vesicles 성과년도 2018 성과 고유번호 JNL-2018-00110188689 학술지명 SMALL ISSN 1613-6810

Modulation of Cerebellar Cortical Plasticity Using Low-Intensity Focused Ultrasound for Poststroke Sensorimotor Function Recovery 성과년도 2018 성과 고유번호 JNL-2018-00110188712 학술지명 NEUROREHABILITATION AND NEURAL REPAIR ISSN 1545-9683

Determination of Optimal Heart Rate Variability Features Based on SVM-Recursive Feature Elimination for Cumulative Stress Monitoring Using ECG Sensor 성과년도 2018 성과 고유번호 JNL-2018-00110188711 학술지명 SENSORS ISSN 1424-8220

Engineering nanoparticle strategies for effective cancer immunotherapy 성과년도 2018 성과 고유번호 JNL-2018-00110188683 학술지명 BIOMATERIALS ISSN 0142-9612

Nanoscale polyelectrolyte complexes encapsulating mRNA and long-chained siRNA for combinatorial cancer gene therapy 성과년도 2018 성과 고유번호 JNL-2018-00110188693 학술지명 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY ISSN 1226-086X

Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging 성과년도 2018 성과 고유번호 JNL-2018-00110188694 학술지명 DRUG DELIVERY ISSN 1071-7544

AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development 성과년도 2018 성과 고유번호 JNL-2018-00110188702 학술지명 MOLECULAR CANCER RESEARCH ISSN 1541-7786

Direct observation of DNA target searching and cleavage by CRISPR-Cas12a 성과년도 2018 성과 고유번호 JNL-2018-00110188682 학술지명 NATURE COMMUNICATIONS ISSN 2041-1723

Graded 6-OHDA-induced dopamine depletion in the nigrostriatal pathway evokes progressive pathological neuronal activities in the subthalamic nucleus of a hemi-parkinsonian mouse 성과년도 2018 성과 고유번호 JNL-2018-00110188708 학술지명 BEHAVIOURAL BRAIN RESEARCH ISSN 0166-4328

Feasibility Study on a Segmented Ferrofluid Flow Linear Generator for Increasing the Time-Varying Magnetic Flux 성과년도 2018 성과 고유번호 JNL-2018-00110188715 학술지명 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY ISSN 1533-4880

PEG-PLA-Coated and Uncoated Radio-Luminescent CaWO4 Micro- and Nanoparticles for Concomitant Radiation and UV-A/Radio-Enhancement Cancer Treatments 성과년도 2018 성과 고유번호 JNL-2018-00110188692 학술지명 ACS BIOMATERIALS SCIENCE & ENGINEERING ISSN 2373-9878

An Implantable Wireless Neural Interface System for Simultaneous Recording and Stimulation of Peripheral Nerve with a Single Cuff Electrode 성과년도 2018 성과 고유번호 JNL-2018-00110188709 학술지명 SENSORS ISSN 1424-8220

A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration 성과년도 2018 성과 고유번호 JNL-2018-00110188696 학술지명 STEM CELLS INTERNATIONAL ISSN 1687-966X

Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment 성과년도 2018 성과 고유번호 JNL-2018-00110188698 학술지명 ACS NANO ISSN 1936-0851

BUBBLE DYNAMICS IN BOILING HISTOTRIPSY 성과년도 2018 성과 고유번호 JNL-2018-00110188706 학술지명 ULTRASOUND IN MEDICINE AND BIOLOGY ISSN 0301-5629

Neutralizing the Detrimental Effect of an N-Hydroxysuccinimide Quenching Reagent on Phosphopeptide in Quantitative Proteomics 성과년도 2018 성과 고유번호 JNL-2018-00110188699 학술지명 ANALYTICAL CHEMISTRY ISSN 0003-2700

Numerical Simulation on the Induced Voltage Across the Coil Terminal by the Segmented Flow of Ferrofluid and Air-Layer 성과년도 2018 성과 고유번호 JNL-2018-00110188714 학술지명 JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY ISSN 1533-4880

K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death 성과년도 2018 성과 고유번호 JNL-2018-00110188703 학술지명 ONCOGENE ISSN 0950-9232

Double-pulse laser illumination method for measuring fast cerebral blood flow velocities in the deep brain using a fiber-bundle-based endomicroscopy system 성과년도 2018 성과 고유번호 JNL-2018-00110188710 학술지명 BIOMEDICAL OPTICS EXPRESS ISSN 2156-7085

Phosphoproteomic analysis reveals PAK2 as a therapeutic target for lapatinib resistance in HER2-positive breast cancer cells 성과년도 2018 성과 고유번호 JNL-2018-00110188700 학술지명 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN 0006-291X

Implication of multivalent aptamers in DNA and DNA-RNA hybrid structures for efficient drug delivery in vitro and in vivo 성과년도 2018 성과 고유번호 JNL-2018-00110188691 학술지명 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY ISSN 1226-086X

Profiling of protein-protein interactions via single-molecule techniques predicts the dependence of cancers on growth-factor receptors 성과년도 2018 성과 고유번호 JNL-2018-00110188681 학술지명 NATURE BIOMEDICAL ENGINEERING ISSN 2157-846X

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