출원등록명	우수한 카이네이즈 저해 활성을 보이는 다양한 치환기를 갖는 피리미딘 유도체
산업재산권 구분	특허	특허구분	출원
출원등록번호	10-2018-0042031	출원등록자	한국과학기술연구원
출원등록국가	대한민국	IPC 코드	C07D 405/12,A61K 31/506,C07D 405/14,A61P 35/00,A61P 25/28,A61P 25/16,A61P 29/00
성과년도	2018	NTIS 성과고유번호	PTO-2018-00210186178

NBIT 융합기술 개발사업(CLC) 과제년도 2018 과제번호 1711079863 연구기관 한국과학기술연구원 연구기간 2018-01-01~2018-12-31

Reinvestigation of an O-Salicylaldehyde Ester Functional Group in Aqueous Buffer and Discovery of a Coumarin Scaffold Probe for Selective N-Terminal Cysteine Labeling 성과년도 2018 성과 고유번호 JNL-2018-00110413637 학술지명 CHEMBIOCHEM ISSN 1439-4227

Rapid and background-free detection of avian influenza virus in opaque sample using NIR-to-NIR upconversion nanoparticle-based lateral flow immunoassay platform 성과년도 2018 성과 고유번호 JNL-2018-00110188762 학술지명 BIOSENSORS & BIOELECTRONICS ISSN 0956-5663

Mass spectrometry-based metabolic signatures of sex steroids in breast cancer 성과년도 2018 성과 고유번호 JNL-2018-00110188758 학술지명 MOLECULAR AND CELLULAR ENDOCRINOLOGY ISSN 0303-7207

Aster glehni Extract Containing Caffeoylquinic Compounds Protects Human Keratinocytes through the TRPV4-PPAR delta-AMPK Pathway 성과년도 2018 성과 고유번호 JNL-2018-00110188763 학술지명 EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE ISSN 1741-427X

Validation of Neurotensin Receptor 1 as a Therapeutic Target for Gastric Cancer 성과년도 2018 성과 고유번호 JNL-2018-00110188761 학술지명 MOLECULES AND CELLS ISSN 1016-8478

Mono-allyloxylated Cucurbit[7]uril Acts as an Unconventional Amphiphile To Form Light-Responsive Vesicles 성과년도 2018 성과 고유번호 JNL-2018-00110188757 학술지명 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ISSN 1433-7851

Effective and sensitive determination of eleven disinfection byproducts in drinking water by DLLME and GC-MS 성과년도 2018 성과 고유번호 JNL-2018-00110188759 학술지명 SCIENCE OF THE TOTAL ENVIRONMENT ISSN 0048-9697

Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents 성과년도 2018 성과 고유번호 JNL-2018-00110188735 학술지명 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ISSN 0223-5234

Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of A beta-induced mitochondrial dysfunction in Alzheimer's disease 성과년도 2018 성과 고유번호 JNL-2018-00110188737 학술지명 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ISSN 0223-5234

Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-beta modulators 성과년도 2018 성과 고유번호 JNL-2018-00110188739 학술지명 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ISSN 0223-5234

Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors 성과년도 2018 성과 고유번호 JNL-2018-00110188740 학술지명 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS ISSN 0960-894X

First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia 성과년도 2018 성과 고유번호 JNL-2018-00110188738 학술지명 JOURNAL OF MEDICINAL CHEMISTRY ISSN 0022-2623

Determination of six iodotrihalomethanes in drinking water in Korea 성과년도 2018 성과 고유번호 JNL-2018-00110188760 학술지명 SCIENCE OF THE TOTAL ENVIRONMENT ISSN 0048-9697

Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs 성과년도 2018 성과 고유번호 JNL-2018-00110188734 학술지명 CHEMICAL BIOLOGY & DRUG DESIGN ISSN 1747-0277

Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds 성과년도 2018 성과 고유번호 JNL-2018-00110188736 학술지명 MOLECULES ISSN 1420-3049

Effective and sensitive determination of eleven disinfection byproducts in drinking water by DLLME and GC-MS 성과년도 2018 성과 고유번호 JNL-2018-00110188759 학술지명 SCIENCE OF THE TOTAL ENVIRONMENT ISSN 0048-9697

Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors 성과년도 2018 성과 고유번호 JNL-2018-00110188740 학술지명 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS ISSN 0960-894X

Aster glehni Extract Containing Caffeoylquinic Compounds Protects Human Keratinocytes through the TRPV4-PPAR delta-AMPK Pathway 성과년도 2018 성과 고유번호 JNL-2018-00110188763 학술지명 EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE ISSN 1741-427X

Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-beta modulators 성과년도 2018 성과 고유번호 JNL-2018-00110188739 학술지명 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ISSN 0223-5234

Mass spectrometry-based metabolic signatures of sex steroids in breast cancer 성과년도 2018 성과 고유번호 JNL-2018-00110188758 학술지명 MOLECULAR AND CELLULAR ENDOCRINOLOGY ISSN 0303-7207

Validation of Neurotensin Receptor 1 as a Therapeutic Target for Gastric Cancer 성과년도 2018 성과 고유번호 JNL-2018-00110188761 학술지명 MOLECULES AND CELLS ISSN 1016-8478

Determination of six iodotrihalomethanes in drinking water in Korea 성과년도 2018 성과 고유번호 JNL-2018-00110188760 학술지명 SCIENCE OF THE TOTAL ENVIRONMENT ISSN 0048-9697

Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds 성과년도 2018 성과 고유번호 JNL-2018-00110188736 학술지명 MOLECULES ISSN 1420-3049

Mono-allyloxylated Cucurbit[7]uril Acts as an Unconventional Amphiphile To Form Light-Responsive Vesicles 성과년도 2018 성과 고유번호 JNL-2018-00110188757 학술지명 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ISSN 1433-7851

First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia 성과년도 2018 성과 고유번호 JNL-2018-00110188738 학술지명 JOURNAL OF MEDICINAL CHEMISTRY ISSN 0022-2623

Reinvestigation of an O-Salicylaldehyde Ester Functional Group in Aqueous Buffer and Discovery of a Coumarin Scaffold Probe for Selective N-Terminal Cysteine Labeling 성과년도 2018 성과 고유번호 JNL-2018-00110413637 학술지명 CHEMBIOCHEM ISSN 1439-4227

Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents 성과년도 2018 성과 고유번호 JNL-2018-00110188735 학술지명 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ISSN 0223-5234

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