국가 R&D 논문 조회
논문명 | Quantitative Evaluation of Cytochrome P450 3A4 Inhibition and Hepatotoxicity in HepaRG 3-D Spheroids | ||
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학술지 | INTERNATIONAL JOURNAL OF TOXICOLOGY | ISSN | 1091-5818 |
SCI 구분 | 01 | 논문구분 | 국외 |
국내외학술지 구분 | 201 | 학술지 구분 | 학술지 |
성과년도 | 2018 | NTIS 성과고유번호 | JNL-2018-00110287248 |
초록 | Predicting drug-drug interactions (DDIs) is an important step during drug development to avoid unexpected side effects. Cytochrome P450 (CYP) 3A4 is the most abundant human hepatic phase I enzyme, whi... |
제브라피쉬 기반 유효성·안전성·약물성 평가 서비스(Zebrafish-based services in efficacy, toxicity, and druggability)
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