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총 게시물 1040

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1040 기술 Candy Maker Mars Plans to Gene-Edit Cacao Plants

CNBC reported that the agreement will allow Mars to access Pairwise technology and a library of plant traits to make DNA adjustments in cacao plants to address disease resistance, drought survival, and other factors.

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NEWSMAX
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1039 기술 Innovative Technique Enables Gene Silencing in Plants to Boost Crop Yields

Viral vector technology, central to this breakthrough, involves the deliberate modification of plant viruses. By excising pathogenic genetic elements, researchers transform these viruses into biological delivery systems capable of transporting specific RNA sequences into plant cells. Historically, this method has shown promise under controlled experimental conditions, enabling the induction of flowering, acceleration in the development of improved varieties, and the alteration of plant architecture to enhance mechanization adaptability. It has also contributed to boosting drought resilience and facilitating the biosynthesis of health-promoting secondary metabolites.

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bioenigineer
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1038 기술 Researchers grow thicker, more realistic lab-grown beef muscle in the lab

The ETH researchers have now succeeded in creating three-dimensional muscle tissue composed of thick fibers from myoblasts. This tissue also more closely resembles natural bovine muscle tissue at the molecular and functional levels; it has the same genes and proteins active as natural bovine muscle tissue and contracts similarly to its natural counterpart. 

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phys.org
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1037 기술 RNA scissors precisely target and remove mutant gene in rapid aging condition in children

A research team led by Dr. Sun-Uk Kim at the Center for Next-Generation Animal Resources, Korea Research Institute of Bioscience and Biotechnology (KRIBB), has successfully developed the world's first precision RNA-targeting therapy for progeria using next-generation gene regulation technology.

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medicalxpress
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1036 기술 Scientists grow novel 'whole-brain' organoid

Johns Hopkins University researchers have grown a novel whole-brain organoid, complete with neural tissues and rudimentary blood vessels—an advance that could usher in a new era of research into neuropsychiatric disorders such as autism.

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medicalxpress
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1035 기술 New cyclic disulfide lipids help stop cancer growth in mice

Researchers at Nagoya University in Japan have developed a lipid nanoparticle that delivers mRNA to cells five times more effectively. By attaching a sulfur-containing ring structure—a cyclic disulfide—to lipid molecules, they found that significantly more mRNA can escape from cell components that normally destroy genetic material. When tested as a cancer vaccine in mice, the new delivery system stopped tumor growth. The study, published in the journal RSC Medicinal Chemistry, demonstrates the first successful use of cyclic disulfide-containing lipids to improve mRNA delivery in animals and suppress tumor growth.
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EurekAlert!
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1034 기술 Mexican neuroscientist identifies glutamate biomarker predicting schizophrenia treatment success

The laboratory's most significant contribution centers on discoveries about glutamate dysfunction in early psychosis. Through sophisticated MRI spectroscopy techniques applied to antipsychotic-naïve patients, Dr. de la Fuente-Sandoval's team identified elevated glutamate levels specifically within the associative striatum. More importantly, they demonstrated that these elevations normalize following effective antipsychotic treatment.

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EurekAlert!
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1033 기술 Researchers discover how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's

When the researchers reanalyzed a prior study of gene expression in the human brain, they found that individuals who died of mild Alzheimer's had microglia with abundant ADGRG1, and mild cognitive impairment—implying that the microglia ate well and kept the disease in check. But in those who died of severe Alzheimer's, the microglia had very little ADGRG1, and the plaques proliferated.

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medicalxpress
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1032 기술 CRISPR Gene Editing Halts Spread of Malaria by Replacing a Single Gene in Mosquitoes

Researchers from UC San Diego and Johns Hopkins have developed a CRISPR-based gene-editing technique that changes one amino acid (L224 to Q224) in mosquitoes, blocking the transmission of malaria parasites without affecting mosquito health.
__This edit targets the FREP1 protein, which is exploited by the parasite to reach the mosquito's salivary glands, thereby stopping infection spread.
__The genetically edited trait can be inherited across mosquito populations, potentially eliminating malaria transmission using a natural allelic-drive approach.__

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technologyNetworks
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1031 기술 A shared five biomarker profile across four major neurodegenerative diseases

The Global Neurodegeneration Proteomics Consortium (GNPC) identified a five-protein panel that predicts APOE ε4 status across multiple neurodegenerative diseases with high accuracy. The study analyzed over 35,000 proteomic assays from 23 global cohorts, revealing disease-specific protein signatures and shared biomarkers. Although findings are correlative, they offer a promising path for discovering disease-modifying therapies, highlighting the importance of global scientific collaboration.

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medicalxpress
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