해외뉴스
(해외) 합성생물학 뉴스
해외뉴스
총 게시물 1009건
| 1009 | 기술 |
N새글
New 'gene gun' design boosts efficiency of plant genetic modification
the researchers designed a new internal barrel for the gene gun—they call it the "Flow Guiding Barrel"—and Connor Thorpe, a doctoral student and 3D-printing hobbyist, printed one for testing. The computer modeling shows a conventional gene gun directs about 21% of loaded particles toward its plant cell targets while a gene gun modified with the Flow Guiding Barrel delivers nearly 100%.
|
| 1008 | 기술 |
N새글
AI-designed inhibitor targets key enzyme to fight prostate cancer drug resistance
In this study, the researchers constructed a high-precision structure model of 3βHSD1 by integrating AlphaFold2 protein structure predictions, molecular dynamics simulations, quantum chemistry calculations and other techniques, and revealed its unique catalytic mechanism and substrate-binding pocket characteristics.
|
| 1007 | 기술 |
64x Bio Unveils AAV Apex Suite to Address Gene Therapy Manufacturing Bottlenecks
64x Bio는 유전자 치료의 주요 병목 현상인 제조 확장성을 해결하기 위해 설계된 고성능 제품 라인인 AAV Apex Suite를 출시했습니다. 이 제품군에는 일시적 감염에 최적화된 현탁액 적응형 HEK293 세포주가 포함되어 있으며, 혈청형과 페이로드에 걸쳐 검증된 E15 vg/L 이상의 역가를 제공합니다. 이 제품은 유전자 및 대사 프로파일링을 사용하여 세포주 엔지니어링 및 배지 배합을 개선하는 VectorSelect 플랫폼에 의해 구동됩니다.
|
| 1006 | 산업 |
Halting Deforestation With Synthetic Biology-Produced Fats
A new method produces palm oil without palm trees by fermenting food industry waste with yeast, significantly cutting carbon emissions (by 96%) and land use (by 99%), while maintaining cost competitiveness. This eco-friendly approach avoids deforestation and biodiversity loss caused by traditional fat sources. Accelerating the use of such sustainable fats requires faster regulatory approval, industrial scaling, and partnerships with major consumer goods companies.
|
| 1005 | 기술 |
Engineered transcription factor-binding arrays for DNA-based gene expression control in mammalian cells
This study presents RE (response element) arrays as a tool to modulate gene expression in mammalian cells, offering an alternative to high-burden overexpression systems. Using TetR and dCas9 gene circuits, the arrays were applied to synthetic gene regulation. The authors developed CTRL, a novel method for assembling long repetitive sequences. CTRL proved robust and efficient, enabling arrays with up to 256 REs and providing insights into TF interactions in mammalian cells.
|
| 1004 | 기술 |
Scientists discover unknown organelle inside our cells by University of Virginia
"This is like discovering a new recycling center inside the cell," said researcher Seham Ebrahim, Ph.D., of UVA's Department of Molecular Physiology and Biological Physics. "We think the hemifusome helps manage how cells package and process material, and when this goes wrong, it may contribute to diseases that affect many systems in the body."
|
| 1003 | 정책 |
N새글
$12M Boost for Aussie Heart & Diabetes Med Tech
The Australian Government is investing $12 million to develop new Australian-made medical devices and medicines for people with cardiovascular disease and diabetes. Fourteen Australian start-ups and innovators will receive funding and commercialisation support to develop improved treatments to manage the complications of cardiovascular disease and type 1 and type 2 diabetes.
|
| 1002 | 기술 |
Liver organoid breakthrough: Generating organ-specific blood vessels
Scientists from Cincinnati Children’s and colleagues based in Japan report achieving a major step forward in organoid technology--producing liver tissue that grows its own internal blood vessels.
|
| 1001 | 기술 |
Guest molecules ride perfect waves in dna droplets—A breakthrough for synthetic biology
Scientists have uncovered a previously unknown type of molecular motion inside DNA-based droplets: instead of spreading randomly, guest molecules advance in an organized wave. This surprising discovery opens the door to understanding how cells might organize internal processes without membranes. Using customizable DNA condensates as experimental models, the team showed how molecular waves emerge through precise DNA interactions. These insights could not only transform our grasp of cellular signaling but may even lay groundwork for treating neurodegenerative diseases by influencing how molecules behave inside aging cells.
|
| 1000 | 기술 |
Five-day vascular organoids speed tissue engineering research
In the study, "Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages," published in Cell Stem Cell, researchers designed a dual-factor program to co-differentiate induced pluripotent stem cells into endothelial and mural fates for rapid vascular-organoid assembly. The authors conclude that orthogonal transcription-factor programming offers a scalable path to tailor-made vascular organoids capable of rapid engraftment and tissue rescue, suggesting future avenues for treating ischemic injury, improving cell-therapy survival and a potentially durable diabetes therapy.
|