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총 게시물 1090

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1090 기술 Yeast-engineered biocatalysis enables stepwise production of MDMA and analogs

Researchers successfully developed a stepwise hybrid bioconversion-biocatalysis strategy using engineered yeast to produce MDMA and its analogs. This is a proof-of-concept route that replaces traditional chemical synthesis, offering a safer and more sustainable alternative. The study validated the end-to-end feasibility but identified two major bottlenecks for future optimization: improving the in vivo $\omega$-transamination drive and enhancing the N-methyltransferase efficiency.

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EurekAlert!
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1089 정책 N새글 Synthetic biology gets IUCN nod as possible nature defender

In the race to slow down the sixth mass extinction, conservation efforts fall broadly into two categories: tackling the threats to biodiversity and helping species cope with them. In both cases, the emerging field of synthetic biology shows significant promise, from the ability to engineer disease resistance in endangered species to providing synthetic alternatives to products derived from particular species, reducing pressure on them. At its recent World Conservation Congress, the global authority on nature, the International Union for Conservation of Nature (IUCN), approved a policy on how best to manage these new technologies and their impacts, potentially either positive or negative, on biodiversity conservation. Members voted in favour of a science-based approach to synthetic biology, rejecting a proposed moratorium that would have disrupted vital research into potentially transformative new tools not only for conservation but also for public health, including efforts to control vector-borne diseases such as malaria.

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Context News
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1088 기술 What is mirror life? Scientists are sounding the alarm

The report concluded that mirror cells could become a reality in the next 10 to 30 years and detailed the potentially devastating consequences if mirror bacteria were released into an environment and spread, evading natural biological controls and acting as dangerous pathogens. Relman said mirror bacteria could potentially evade critical parts of plant, animal and human immune systems, which would have difficulty detecting or killing them. Once inside a human, a mirror bacteria could hypothetically replicate to extremely high levels in the body, causing its host to experience something similar to septic shock. Potential medical countermeasures — including most antibiotics — are chiral, meaning they likely would not be effective on mirror bacteria.

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CNN Science
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1087 정책 Scientists are modifying wildlife DNA. Should these species be released into nature?

This week, one of the world's largest conservation groups will weigh in on how those gene-editing tools should be used to aid the planet's declining ecosystems and threatened species — and, critically, whether genetically modified plants and animals should be allowed into the wild. At the heart of the debate is a proposed moratorium, sponsored by a coalition of environmental groups at a meeting of the International Union for the Conservation of Nature (IUCN), that would temporarily ban scientists from releasing genetically modified species into the wild. They're preaching precaution. On the other side are scientists and conservation groups who argue that everything should be on the table in the fight against worsening rates of extinction. That includes synthetic biology — the catch-all term used for a suite of genetic tools that scientists use to alter or engineer living cells.

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NPR
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1086 산업 Congratulations to Dr. Ilana Kolodkin-Gal of the Scojen Institute for Synthetic Biology on winning a BSF-NSF research grant

Congratulations to Dr. Ilana Kolodkin-Gal of the Scojen Institute for Synthetic Biology on winning a BSF-NSF research grant. This study will investigate the role of invasive and pathogenic strains of intestinal bacteria in disrupting the intestinal barrier, which is associated with Inflammatory Bowel Diseases (IBD). The researchers will create a novel mucin-on-a-chip specifically designed for IBD research to gain insights into limiting the bacterial drivers of the disease. This work represents a paradigm shift, proposing that targeted therapies in gut bacterial communities can be used to treat chronic inflammatory disorders of the gastrointestinal tract.

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EurekAlert!
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1085 산업 Caravel Bio Wins $7.8M NSF Grant to Pioneer Next-Generation Protein Engineering

Caravel Bio, the first joint platform for protein discovery and delivery that enables new applications of synthetic biology, today announces its selection for a $7.8M award from the U.S. National Science Foundation Directorate for Technology, Innovation and Partnerships (NSF TIP). The award assembles a team of world-class engineers to create tools for building proteins with novel chemistries, train more advanced machine learning models on the resulting datasets, and develop new, innovative products across industries.

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HIT Consultant
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1084 기술 Synthetic biology reprograms plant–microbe partnerships for resilient agriculture

By integrating engineering principles with plant biology, this review highlights how redesigned genetic pathways and plant-based biosensors can deepen understanding of plant responses to both harmful and beneficial microbes. The authors emphasize that these approaches could reshape sustainable agriculture, improving crop resilience to pathogens, drought, and other stresses while reducing reliance on chemical inputs.

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EurekAlert!
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1083 정책 Reactions as IUCN Congress votes to adopt Policy on Synthetic Biology, rejects genetic engineering moratorium

Following the vote at the IUCN World Conservation Congress, members have rejected a moratorium on genetic engineering of wild species (Motion 133) and adopted the IUCN Policy on Synthetic Biology (Motion 087), a move observers see as a signal of support for a science-based, case-by-case approach to innovation in conservation.

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EnviroNews Nigeria
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1082 기술 Scientists Create Artificial Neuron That “Speaks” the Language of the Brain

Engineers at the University of Massachusetts Amherst have developed an artificial neuron that behaves strikingly like its natural counterpart. The breakthrough builds on earlier research in which the team created protein nanowires from electricity-producing bacteria. Their new discovery suggests the possibility of designing computers that are far more energy-efficient and capable of directly interacting with living cells. “Ours register only 0.1 volts, which is about the same as the neurons in our bodies,” says Yao. There are a wide range of applications for Fu and Yao’s new neuron, from redesigning computers along bio-inspired, and far more efficient principles, to electronic devices that could speak to our bodies directly.

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SciTechDaily
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1081 기술 Developing a transparent artificial cornea for people with visual impairments

Damage to the cornea affects millions of people worldwide. Empa researchers are working on a transparent, biocompatible implant from the 3D printer. This allows defects to be repaired seamlessly and permanently. The project could now be started thanks to a generous donation from a foundation.

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News-Medical
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