합성생물학 역사
합성생물학 역사
합성생물학 역사
A brief history of
synthetic biology
synthetic biology
- Timeline -
- 출처
- Nature Reviews Microbiology 12(5), 381-390 (2014)
- The second decade of synthetic biology_2010-2020
2010년 이후
- 2019
-
- Full synthesis of E. coli genome
- Carbon fixation in engineered E. coli
- Gene circuits with designed proteins
- Synthetic production of cannabinoids
- 2018
-
- CAR-T cells with logic control
- Yeast with synthetically fused chromosomes
- Self-organizing multicellular structures
- 2017
-
- Synthesis of 5 more yeast chromosomes
- CRlSPR-based rapid diagnostics
- 2016
-
- In vivo event recorders
- Synthesis of a reduced mycoplasma genome
- Cello CAD for E. coli logic gates
- 2015
-
- E. coli dependent on synthetic amino acids/li>
- Biosynthesis of opioids from yeast
- 2014
-
- Bacteria that sense and record in the gut Cell-free paper-based sensors and logic
- E. coli engineered with 6 bases of DNA
- Synthesis of a yeast chromosome
- 2013
-
- Biosynthetic production of artemisinin
- Genomically recoded E. coli
- 2012
-
- DNA used for data storage
- Refactored nitrogen fixation cluster
- Whole cell simulation of a mycoplasma
- 2011
-
- Phage-based continuous evolution
- Bacterial growth in stripe patterns
- 2010
-
- Synchronized bacterial oscillators
- Synthetic mycoplasma genome
Key to coloured boxes
- black
- technical or cultural milestones
- green
- synthetic biology in metabolic engineering
- blue
- therapeutic applications
- red
- circuit engineering
- puple
- whole genome engineering
Acronym
- E. coli
- Escherichia coli
- iGEM
- International Genetically Engineered Machine
- MAGE
- multiplex automated genome engineering
- SB1.0.
- Synthetic Biology 1.0
- MIT
- Massachusetts Institute of Technology
- S. cerevisiae
- Saccharomyces cerevisiae