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Global News

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1028 기술 21st.BIO Unveils Precision Fermentation Initiative for Bovine Alpha-Lactalbumin

Alpha-lactalbumin is a functional milk protein known for its richness in essential amino acids, ease of digestion, and benefits related to immune and cognitive development. Presently, bovine α-lac is utilized in infant nutrition, functional foods, and health-oriented applications. 21st.BIO is working to optimize the Novonesis strain for industrial fermentation and commercialization, with the goal of making precision fermented α-lac competitively priced compared to its bovine-derived equivalent.

Collection Date
Source
synbiobeta
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1027 기술 Real milk proteins, no cows: Engineered bacteria pave the way for vegan cheese and yogurt

The team carried out structural analysis, calcium-binding tests, and simulated gastrointestinal digestion of the derived αs1-casein. The results indicated that both the phosphorylated and phosphomimetic caseins of bacterial origin had a high calcium-binding capacity, and their digestibility and structure were comparable to that of cattle-derived casein.

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Source
phys.org
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1026 기술 Oligo pools to power innovation in protein engineering

Agilent’s SurePrint DNA synthesis platform enables researchers to create custom oligo pools for protein engineering and gene assembly, supporting advances in next-generation therapeutics.
__Integration of AI-based tools like AlphaFold and automated gene assembly techniques is lowering the cost and complexity of protein design.
__These innovations are democratizing access to synthetic biology, allowing researchers to efficiently design, build, test, and iterate protein sequences.__

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Source
SelectScience
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1025 기술 Researchers turn food waste into biodegradable plasti

Researchers at Binghamton University have developed a method to convert food waste into biodegradable plastic using Cupriavidus necator bacteria, offering an eco-friendly solution to food and plastic waste.
__Their process uses fermented food waste as a carbon source and yields polyhydroxyalkanoate (PHA) plastic, with up to 90% harvestable for packaging.
__The method is cost-effective, scalable, and flexible with various food waste types, and the leftover residue may be used as organic fertilizer.__

Collection Date
Source
phys.org
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1024 기술 This New Bioplastic Is Clear Flexible and Stronger Than Oil-Based Plastic. And It’s Made by Microbes

The research team developed a scalable, single-step biofabrication method by incorporating hexagonal boron nitride nanosheets into bacterial cellulose, creating a hybrid material with superior strength and thermal properties. Unlike traditional alignment techniques, their approach is low-cost, reproducible, and continuous without damaging the structure or requiring binders. This innovation enables on-site integration of various nanomaterials, paving the way for applications in smart packaging, conductive fibers, and bioelectronics.

Collection Date
Source
ZEMSCIENCE
Date
1023 기술 World-First Gene Editing Trial for Rare Genetic Disease at UConn Health

희귀 유전 대사 질환인 '글리코겐축적병 1a형'을 유전자 가위로 치료하는 세계 최조 인간대상 GSD1a 임상 시험에서 첫번째 환자에게 투약하였음. 이 치료법은 CRISPR-Cas 9 기반 정밀 유전자 기위 기술에서 발전된 뉴클레오타이드 편집 기법으로, GSD1a의 주요 돌연변이를 교정하여 근본적이고 지속적인 치료 효과를 목표로 함. 

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Source
uconn today
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1022 기술 Plants engineered for optimal biofuel production

Researchers at the University of Missouri used Arabidopsis to study how genetic modifications affect plant metabolism and oil production for biofuel. They discovered unexpected results, including a simultaneous increase in both oil and protein content and an energy-wasting cycle that breaks down newly produced oil. These insights could lead to more efficient engineering of oil-rich plants like camelina for sustainable bioenergy.
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phys.org
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1021 기술 Scientists Develop New Method to Create Potential Replacement for Plastic

Researchers from the University of Houston and Rice University have developed a scalable, single-step method to produce strong and flexible bacterial cellulose sheets as a sustainable alternative to plastic. By incorporating boron nitride nanosheets and using a custom rotational culture device, they enhanced the material's mechanical and thermal properties. This eco-friendly innovation has potential applications in packaging, textiles, electronics, and more, contributing to a future less dependent on petroleum-based plastics.

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The University Network
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1020 기술 Data mining uncovers treasure-trove of previously 'untouchable' proteins for drug development

A new Science study expands the range of druggable targets using molecular glue degraders, which can now bind to a broader set of protein surface motifs beyond the previously limited beta-hairpin loop. These degraders manipulate cereblon (CRBN) to tag disease-related proteins for degradation via the ubiquitin-proteasome pathway. This approach opens new therapeutic avenues for previously "undruggable" proteins, including VAV1, which is linked to autoimmune and chronic inflammatory diseases.

Collection Date
Source
phys.org
Date
1019 기술 Gene-editing platform could boost anti-cancer immune responses

Researchers developed a gene-editing platform that enables T cells to release anti-cancer compounds only within tumors. This minimizes harmful side effects and boosts the effectiveness of immunotherapy against solid tumors. The breakthrough could lead to safer, more effective treatments for cancers like sarcomas and carcinomas.

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medicalxpress
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