Synthetic biologists at Rice University say they have developed the first method for observing the real-time activity of some of most common signal-processing circuits in bacteria, including deadly pathogens that use the circuits to increase their virulence as well as to develop antibiotic drug resistance. Two-component systems are sensory circuits bacteria use to react to their surroundings and survive. Bacteria use the circuits, which are also known as signal transduction pathways, to sense an “unrivaled range of stimuli” from light and metal ions to pH and even messages from their friends and neighbors, said Rice bioengineering professor Jeffrey Tabor, PhD.

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GEN, 22.08.26.

https://www.genengnews.com/topics/translational-medicine/infectious-diseases/synthetic-biologists-use-novel-tool-to-see-signal-processing-in-real-time/